陈缙泉

2007/08-2012/08，美国俄亥俄州立大学，博士

2003/09-2007/06，南京大学，学士

2015/10-至今，华东师范大学，精密光谱科学与技术国家重点实验室，研究员

2013/09-2015/09，美国埃默里大学，博士后研究员，合作导师：Tianquan Lian

2012/08-2013/08，美国蒙大拿州立大学，博士后研究员, 合作导师：Bern Kohler

陈缙泉，现任华东师范大学精密光谱科学与技术国家重点实验室研究员。2003-2007年在南京大学化学化工学院进行了本科阶段的学习，后于2007-2012年在美国俄亥俄州立大学 (The Ohio State University) 取得博士学位。然后于2012-2013年在美国蒙大拿州立大学 (Montana State University) 和2013-2015年在埃默里大学 (Emory University) 进行了两阶段博士后研究工作。主要研究方向是采用飞秒瞬态光谱研究生物大分子中激发态动力学过程，近年来工作已在 Science, Journal of the American Chemical Society, Chemical Science, Journal of Physical Chemistry，Physical Chemistry Chemical Physics等期刊发表，目前共发表论文50余篇。2019年入选上海市青年科技启明星计划。

研究兴趣：

激发态超快动力学，生物光子学, 生物传感, 生物探针, 生物成像, DNA损伤与修复, 飞秒激光光谱

分子光谱学分析

1.国家自然科学基金面上项目，21873030，化学修饰核酸分子电子激发态动力学特性的研究，主持

2.国家自然科学基金重大研究计划重点，91850202，新型宽场超分辨及超高速光学显微成像基础研究与应用，参与

3.国家自然科学基金面上项目，11674101，基于宽带飞秒瞬态光谱对DNA电子激发态的研究，主持

42.Fu, L.; Wang, Z.; Liu,Y.; Wang, X.; Xu, R.; Liu, W.*; Chen, J.*; Xu, J. Observation of Triplet nπ* State in Ultrafast Intersystem Crossing of 6-Azathymine. Journal of Photochemistry and Photobiology A: Chemistry 2020, 396, 112491.

41.Xu, R.; Hu, Z.; Wang, X.; Liu, Y.; Zhou, Z.; Xu, J.; Sun, Z.; Sun, H.; Chen, J.* Intramolecular Charge Transfer in 5-Halogen Cytidines Revealed by Femtosecond Time-resolved Spectroscopy. J. Phys. Chem. B 2020, 124, 2560-2567.

40.Chen, Z.; Liu, Y.; He, X.*; Chen, J.* Ultrafast excited state dynamics of biliverdin dimethyl Ester coordinate with zinc ions. Chinese Journal of Chemical Physics2020,33 (1), 69-74.

39.Cao, X.; Zhang, C.;   Gao, Z.; Liu, Y.; Zhao, Y.; Yang, Y.; Chen, J.*; Jimenez, R.*; Xu, J.   Ultrafast internal conversion dynamics of bilirubin bound to unag and   its n57a mutant. Phys. Chem. Chem. Phys.2019, 21, 2365-2371.

38.Zhou,   Z.; Wang, X.; Chen, J.*; Xu, J. Direct observation of intramolecular   charge transfer state in epigenetic nucleobase n6-methyladenine. Phys. Chem. Chem. Phys.2019, 21, 6878-6885.

37.Zhou,   Z.; Hu, Z.; Zhang, X.; Jia, M.; Wang, X.; Su, H.; Sun, H.; Chen, J.*;   Xu, J. Ph controlled intersystem crossing and singlet oxygen generation   of 8-azaadenine in aqueous solution. ChemPhysChem 2019, 20, 757-765.

36.He,   X.; Zhao, L.; Zhou, Z.; Zhang, S.; Pan, H.; Chen, J.*; Xu, J.* Near   unity charge separation efficiency leads to pure ultraviolet emission  in  few layer graphene nanosheets. Nanotechnology 2019, 30, 295201.

35.He,   X.; Zhang, S.; Pan, H.; Chen, J.*; Xu, J.* Horizontally aggregation of   monolayer reduced graphene oxide under deep uv irradiation in  solution. Nanoscale Research Letters 2019, 14, 117.

34.Wang,   X.; Yu, Y.; Zhou, Z.; Liu, Y.; Yang, Y.; Xu, J.; Chen, J.* Ultrafast   intersystem crossing in epigenetic DNA nucleoside   2′-deoxy-5-formylcytidine. J. Phys. Chem. B 2019, 123, 5782-5790.

33.Wang,   F.; He, X.; Sun, L.; Chen, J.*; Wang, X.; Xu, J.; Han, X.* Engineering   an n-doped tio2@n-doped c butterfly-like nanostructure with long-lived   photo-generated carriers for efficient photocatalytic selective amine   oxidation. Journal of Materials Chemistry A 2018, 6, 2091-2099.

32.Han, X.*; He, X.; Sun, L.; Han, X.; Zhan, W.; Xu, J.; Wang, X.; Chen, J.*  Increasing  effectiveness of photogenerated carriers by in situ  anchoring of cu2o  nanoparticles on a nitrogen-doped porous carbon  yolk–shell  cuboctahedral framework. ACS Catalysis 2018, 3348-3356.

31.He,   H.; Xia, Y.; Qi, Y.; Wang, H.-Y.; Wang, Z.; Bao, J.; Zhang, Z.; Wu,   F.-G.; Wang, H.; Chen, D., et al. A water-soluble, green-light   triggered, and photo-calibrated nitric oxide donor for biological   applications. Bioconjugate Chem.2018, 29, 1194-1198.

30.Pilles,   B. M.; Maerz, B.; Chen, J.; Bucher, D. B.; Gilch, P.; Kohler, B.;   Zinth, W.; Fingerhut, B. P.; Schreier, W. J. Decay pathways of thymine   revisited. J. Phys. Chem. A 2018, 122, 4819-4828.

29.Wang, X.; Zhou, Z.; Tang, Y.; Chen, J.*;   Zhong, D.; Jianhua, X. Excited state decay pathways of   2′-deoxy-5-methylcytidine and deoxycytidine revisited in solution: A   comprehensive kinetic study by femtosecond transient absorption. J. Phys. Chem. B 2018, 122, 7027-7037.

28.Zhao, L.; Chen, J.*;   He, X.; Yu, X.; Yan, S.; Zhang, S.; Pan, H.; Xu, J. Solvent induced   fluorescence enhancement of graphene oxide studied by ultrafast   spectroscopy. Chem. Phys.2018, 508, 1-6.

27.He,   H.; Liu, Y.; Zhou, Z.; Guo, C.; Wang, H.-Y.; Wang, Z.; Wang, X.;  Zhang,  Z.; Wu, F.-G.; Wang, H., et al. A photo-triggered and  photo-calibrated  nitric oxide donor: Rational design, spectral  characterizations, and  biological applications. Free Radical Biol. Med.2018, 123, 1-7.

26.Luo,   X.; Yang, H.; Wang, H.; Ye, Z.; Zhou, Z.; Gu, L.; Chen, J.; Xiao, Y.;   Liang, X.; Qian, X., et al. Highly sensitive hill-type small-molecule  ph  probe that recognizes the reversed ph gradient of cancer cells. Anal. Chem.2018, 90, 5803-5809.

25.Jia, M.*; Zhou, Z.; Lv, M.; Chen, J.*  Dual  excited state deactivation pathways in tpz2: A centrosymmetric dye   with both high fluorescence and triplet state quantum yield. Chin. Chem. Lett.2018, 29, 1486-1488.

24.Yang,   J.; Liu, X.; Zhang, Y.; Zheng, X.; He, X.; Wang, H.; Yue, F.; Braun,   S.; Chen, J.; Xu, J., et al. Comprehensive understanding of  heat-induced  degradation of triple-cation mixed halide perovskite for a  robust solar  cell. Nano Energy 2018, 54, 218-226.

23.Feng,   E.; Zheng, T.; He, X.; Chen, J.; Tian, Y. A novel ternary   heterostructure with dramatic sers activity for evaluation of pd-l1   expression at the single-cell level. Science Advances 2018, 4, eaau3494.

22.Gong,   T.; Li, P.; Sui, Q.; Chen, J.; Xu, J.; Gao, E.-Q. A stable   electron-deficient metal–organic framework for colorimetric and   luminescence sensing of phenols and anilines. Journal of Materials Chemistry A 2018, 6, 9236-9244.

21.Zhou, Z.; Zhou, X.; Wang, X.; Jiang, B.*; Li, Y.*; Chen, J.*; Xu, J. Ultrafast excited-state dynamics of cytosine aza-derivative and analogues. J. Phys. Chem. A 2017, 121, 2780-2789.

20.Zhao,   L.; Yu, X.; Zhang, S.; He, X.; Li, L.; Jia, M.; Chang, M.; Pan, H.;   Chen, J.; Wang, W., et al. The phosphorescence and  excitation-wavelength  dependent fluorescence kinetics of large-scale  graphene oxide  nanosheets. RSC Advances 2017, 7, 22684-22691.

19.Han, X.; He, X.; Wang, F.; Chen, J.*; Xu, J.; Wang, X.; Han, X.* Engineering an n-doped cu2o@n-c interface with long-lived photo-generated carriers for efficient photoredox catalysts. Journal of Materials Chemistry A 2017, 5, 10220-10226.

18.Xing,   X.; Zhao, L.; Zhang, Z.; Fang, L.; Fan, Z.; Liu, X.; Lin, X.; Xu, J.;   Chen, J.; Zhao, X., et al. Photoinduced terahertz conductivity and   carrier relaxation in thermal-reduced multilayer graphene oxide films. J. Phys. Chem. C 2017, 121, 2451-2458.

17.Pettinger,   N. W.; Williams, R. E. A.; Chen, J.; Kohler, B. Crystallization   kinetics of cerium oxide nanoparticles formed by spontaneous,   room-temperature hydrolysis of cerium(iv) ammonium nitrate in light and   heavy water. Phys. Chem. Chem. Phys.2017, 19, 3523-3531.

16.Chang,   M.; Li, L.; Hu, H.; Hu, Q.; Wang, A.; Cao, X.; Yu, X.; Zhang, S.;  Zhao,  Y.; Chen, J., et al. Using fractional intensities of  time-resolved  fluorescence to sensitively quantify nadh/nad+ with  genetically encoded  fluorescent biosensors. Sci. Rep.2017, 7, 4209.

15.Lei,   Z.; Yue, P.; Wang, X.; Li, X.; Li, Y.; He, H.; Luo, X.; Meng, X.;  Chen,  J.*; Qian, X., et al. Tpz, a bright centrosymmetric two-photon  scaffold  for bioimaging. Chem. Commun.2017, 53, 10938-10941.

Before join ECNU:

14.Chen,   J.; Wu, K.; Rudshteyn, B.; Jia, Y.; Ding, W.; Xie, Z.-x.; Batista, V.   S.; Lian, T. Ultrafast photo-induced interfacial proton coupled  electron  transfer from cdse quantum dots to 4, 4'-bipyridine. J. Am. Chem. Soc.2016, 138, 884-892.

13.Wu,   K.; Liang, G.; Kong, D.; Chen, J.; Chen, Z.; Shan, X.; McBride, J. R.;   Lian, T. Quasi-type ii cuins 2/cds core/shell quantum dots. Chem. Sci.2016, 7, 1238-1244.

12.Jia,   Y.; Chen, J.; Wu, K.; Kaledin, A. L.; Musaev, D. G.; Xie, Z.; Lian, T.   Enhancing photo-reduction quantum efficiency using quasi-type ii   core/shell quantum dots. Chem. Sci.2016, 7, 4125-4133.

11.Li,   Q.; Wu, K.; Chen, J.; Chen, Z.; McBride, J. R.; Lian, T.   Size-independent exciton localization efficiency in colloidal cdse/cds   core/crown nanosheet type-i heterostructures. ACS Nano 2016, 10, 3843-3851.

10.Wu,   K.; Hill, L. J.; Chen, J.; McBride, J. R.; Pavlopoulos, N. G.; Richey,   N. E.; Pyun, J.; Lian, T. Universal length-dependence of rod-to-seed   exciton localization efficiency in type i and quasi type ii cdse@ cds   nanorods. ACS nano 2015, 9,4591-4599.

9.Chen, J.; Zhang, Y.; Kohler, B. Excited states in DNA strands investigated by ultrafast laser spectroscopy. Top Curr Chem 2015, 356, 39-87.

8.Chen, J.; Kohler, B. Base stacking in adenosine dimers revealed by femtosecond transient absorption spectroscopy. J. Am. Chem. Soc.2014, 136, 6362-6372.

7.Chen,   J.; Zhang, Y.; Kohler, B. Excited states in DNA strands investigated  by  ultrafast laser spectroscopy. Springer Berlin Heidelberg: 2014; pp   1-49.

6.Liu,   R.; Dandu, N. K.; Chen, J.; Li, Y.; Li, Z.; Liu, S.; Wang, C.; Kilina,   S.; Kohler, B.; Sun, W. Influence of different diimine (n^ n) ligands  on  the photophysics and reverse saturable absorption of heteroleptic   cationic iridium (iii) complexes bearing cyclometalating   2-{3-[7-(benzothiazol-2-yl) fluoren-2-yl] phenyl} pyridine (c^ n)   ligands. J. Phys. Chem. C2014, 118, 23233-23246.

5.Zhang, Y.; Chen, J.; Kohler, B. Hydrogen bond donors accelerate vibrational cooling of hot purine derivatives in heavy water. The journal of physical chemistry. A2013, 117, 6771-80.

4.Chen,   J.; Thazhathveetil, A. K.; Lewis, F. D.; Kohler, B. Ultrafast   excited-state dynamics in hexaethyleneglycol-linked DNA homoduplexes   made of a· t base pairs. J. Am. Chem. Soc.2013, 135, 10290-10293.

3.Zhang,   Y.; Dood, J.; Beckstead, A.; Chen, J.; Li, X.; Burrows, C. J.; Lu, Z.;   Matsika, S.; Kohler, B. Ultrafast excited-state dynamics and  vibrational  cooling of 8-oxo-7, 8-dihydro-2’-deoxyguanosine in d2o. J. Phys. Chem. A2013, 117, 12851–12857.

2.Pan,   Z. Z.; Chen, J. Q.; Schreier, W. J.; Kohler, B.; Lewis, F. D. Thymine   dimer photoreversal in purine-containing trinucleotides. J. Phys. Chem. B2012, 116, 698-704.

1.Chen,   J.; Kohler, B. Ultrafast nonradiative decay by hypoxanthine and  several  methylxanthines in aqueous and acetonitrile solution. Phys. Chem. Chem. Phys.2012, 14, 10677-10682.