Xuying

2019.08-2023.08       Case Western ReserveUniversity (US),    Advisor: Dr. Fu-Sen Liang                                              

2016.09-2019.06       University of Chinese Academy of Sciences,  Advisor: Dr. Guangjun Nie                                            2016.09-2019.01       University of Copenhagen (Denmark),        Advisor: Dr. Ken Howard                                   

2012.09-2016.09       Qingdao University

2024.09-now, East China Normal University, School of Pharmacy, professor

2023.08-2024.08, University of Pennsylvania, Postdoctoral Researcher                                                                                                           PI: Dr. Drew Weissman (2023 Nobel Laureate in Physiology or Medicine)                       

My research covers from developing chemically-inducible CRISPR tools for site-specific DNA/RNA epigenetic editing, mRNA medicine development (including mRNA-based CRISPR-mediated RNA editing for the treatment of hereditary diseases and mRNA vaccine) to drug-delivery system developement and nanomedicine for cancer therapy. My reseasrch interest mainly includes developing mRNA medicine and introducing mRNA-based CRISPR RNA editing technology to biological and clinical applications.

1. mRNA-based CRISPR-mediated RNA epigentic editing

2. mRNA-based CRISPR-mediated RNA editing for the treatment of genetic disease

3. mRNA medicine, including mRNA vaccine and protein replacement therapy