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周锋

教授

化学与分子工程学院      

个人资料

  • 部门: 化学与分子工程学院
  • 毕业院校: 华东师范大学
  • 学位: 博士
  • 学历: 研究生
  • 邮编: 200062
  • 联系电话: 15921579677
  • 传真:
  • 电子邮箱: fzhou@chem.ecnu.edu.cn
  • 办公地址: 化学馆C305室
  • 通讯地址: 上海市普陀区中山北路3663号华东师范大学化学馆C305室

教育经历

2005.9–2009.6, 四川师范大学, 材料化学, 学士

2009.92014.6, 华东师范大学, 有机化学, 博士, 导师: 周剑

2014.72017.12, 华东师范大学, 化学与分子工程学院, 讲师

2017.122021.12, 华东师范大学, 化学与分子工程学院, 副教授

2021.12今, 华东师范大学化学与分子工程学院教授(破格晋升)


工作经历

个人简介

社会兼职

研究方向

    主要围绕化学固定二氧化碳开展研究工作,探索二氧化碳参与的不对称催化新反应,通过开发更为高效的催化体系,基于电化学或不对称串联反应等策略,实现手性环碳酸酯或羧酸等系列高附加值化合物的高选择性合成。


招生与培养


开授课程

本科生教学

2016年至今   担任本科生《有机化学实验》教学工作

2018年至今   开设本科生选修课程《化学中的人类文明》

2019年至今   担任本科生基础必修课程《有机化学》教学工作


研究生教学

2016年至今   担任《实验室安全与法律法规》研究生必修课程教学工作

2018年至今   担任《不对称催化》研究生专业选修课程教学工作

科研项目

主持项目情况:


1. 国家重点研发计划“环境友好的土壤、粮食熏蒸处理新技术及产品研发”子课题负责人,2023

2. 国家自然科学基金面上项目,22171090,基于电化学的碳氢键或碳氟键与二氧化碳的羧化反应研究,2021

3. 国家自然科学基金面上项目,21871090,二氧化碳作为 C1 合成子的不对称催化反应研究,2018

4. 国家自然科学基金青年基金项目,21502053,手性硫缩醛/酮的不对称催化合成研究,2015

5. 巴斯夫新材料有限公司横向合作项目,2021

6. 巴斯夫新材料有限公司横向合作项目,2020

学术成果

1.       Z. Zhang, Y. Sun, Y. Gong, D. Tang, H. Luo, Z. Zhao, F. Zhou,* X. Wang* and J. Zhou* Enantioselective propargylic amination and related tandem sequences to α-tertiary ethynylamines and azacycles. Nat. Chem. 2024, 10.1038/s41557-024-01479-z.

2.       P.-W. Xu, F. Zhou,* Lei Zhu* and J. Zhou*,Catalytic desymmetrization reactions to synthesize all-carbon quaternary stereocentresNat. Synth. 20232, 1020–1036.

3.     Y. Gong, C. Wang, F. Zhou,* K. Liao, X.-Y. Wang, Y. Sun, Y.-X. Zhang, Z. Tu, X. Wang,* and J. Zhou*, Sulfonyl-PYBOX Ligands Enable Kinetic Resolution of α-Tertiary Azides by CuAAC. Angew. Chem. Int. Ed.202362, e202301470.

Description unavailable

4.     X.-Y. Cui, Z.-T. Ye, H.-H. Wu,* C.-G. Ji,* F. Zhou* and J. Zhou, Au(I)-Catalyzed Formal Intermolecular Carbene Insertion into Vinylic C(sp2)H Bonds and Allylic C(sp3)H BondsACS Catal.202313, 15541561.

5.          Z.-P. Zhao, H.-R. Lin, Z. Zhang, X.-T. Gao, C.-B. Ji,* J. Zhou, and F. Zhou*A Highly Stereoselective Redox Isomerization-Reductive Deuteration Sequence of Propargyl Amines to α‑Deuterated Amino Acids.Org. Lett.202325, 78957899.

6.              H. Luo, J. Ren, Y. Sun, Y.-L. Liu, F. Zhou,* G.-Y. Shi,* and Jian Zhou, Recent advances in chemical fixation of CO2 based on flow chemistryChin. Chem. Lett.202334, 107782.

7.              X.-Y. Cui, F. Zhou,* H.-H. Wu* and J. Zhou*, Asymmetric Tandem Reactions Achieved by Chiral Amine & Gold(I) Cooperative Catalysis. Chin. J. Org. Chem.202242, 3033-3050.

8.          B.-W. Pan, Y. Shi, S.-Z. Dong, J.-X. He, B.-S. Mu, W.-B. Wu, Y. Zhou,* F. Zhou* and J. Zhou*, Highly stereoselective synthesis of spirocyclopropylthiooxindoles and biological evaluationOrg. Chem. Front.20229, 2640–2646.

Graphical abstract:Highly stereoselective synthesis of spirocyclopropylthiooxindoles and biological evaluation

9.  Z. Zhang, Z.-H. Zhang, F. Zhou,* and Jian Zhou, Catalytic Enantioselective Transfer HydrogenationCarboxylative Cyclization to 4‑Fluoroalkyl 2‑Oxazolidinone with CO2 as the C1 Synthon. Org. Lett. 202123, 27262730.

10.     C.-W. Lei, B.-S. Mu, F. Zhou,* J.-S. Yu,* Y. Zhou* and J. Zhou, Organocatalytic enantioselective reactions involving prochiral carbocationic intermediatesChem. Commun.,202157, 9178.

Graphical abstract:Organocatalytic enantioselective reactions involving prochiral carbocationic intermediates

11.   K. Liao, Y. Gong, R.-Y. Zhu, C. Wang, F. Zhou* and J. Zhou* Highly Enantioselective CuAAC of Functional Tertiary Alcohols Featuring an Ethynyl Group and Their Kinetic Resolution. Angew. Chem. Int. Ed.,202160, 8488–8493.

Description unavailable

12.      X.-T. Gao, Z. Zhang, X. Wang, J.-S. Tian, S.-L. Xie, F. Zhou* and J. Zhou, Direct electrochemical defluorinative carboxylation of alpha-CF3 alkenes with carbon dioxideChem. Sci.202011, 10414-10420.

Graphical abstract:Direct electrochemical defluorinative carboxylation of α-CF3 alkenes with carbon dioxide

13.       F. Zhou,* L. Zhu,* B.-W. Pan, Y. Shi, Y.-L. Liu and J. Zhou* Catalytic enantioselective construction of vicinal quaternary carbon stereocenters. Chem. Sci.202011, 9341-9365.

Graphical abstract:Catalytic enantioselective construction of vicinal quaternary carbon stereocenters

14.   S.-L. Xie, X.-T. Gao, H.-H. Wu,* F. Zhou,* and J. Zhou, Direct Electrochemical Defluorinative Carboxylation of gemDifluoroalkenes with Carbon DioxideOrg. Lett.202022, 8424-8429.

15.   C. Wang, R.-Y. Zhu, K. Liao, F. Zhou,* and J. Zhou*, Enantioselective Cu(I)-Catalyzed Cycloaddition of Prochiral Diazides with Terminal or 1-IodoalkynesOrg. Lett.,  202022, 1270-1274.

16.       C. Wang, F. Zhou,* J. Zhou,* Recent Advances in the Enantioselective Copper(I)-Catalyzed Azide-Alkyne Cycloaddition ReactionChin. J. Org. Chem.,202040, 3065-3077.

 

17.     Y. Shi, B.-W. Pan, Y. Zhou,* J. Zhou, Y.-L. Liu and F. Zhou* Catalytic enantioselective synthesis using carbon dioxide as a C1 synthonOrg. Biomol. Chem.202018, 8597-8619.

Graphical abstract:Catalytic enantioselective synthesis using carbon dioxide as a C1 synthon

18.       S. Xie, X. Gao, F. Zhou*, H. Wu*, J. Zhou*, Enantioselective carboxylative cyclization of propargylic alcohol with carbon dioxide under mild conditionsChin. Chem. Lett. 202031, 324-328.

19.     X.-T. Gao, S.-L. Xie, F. Zhou*, H.-H. Wu*, J. Zhou*, Multifunctional 1,3-diphenylguanidine for the carboxylative cyclization of homopropargyl amines with CO2 under ambient temperature and pressure.Chem. Commun.201955, 14303-14306.

Graphical abstract:Multifunctional 1,3-diphenylguanidine for the carboxylative cyclization of homopropargyl amines with CO2 under ambient temperature and pressure

20.   S.-L. Xie, X.-Y. Cui, X.-T. Gao, F. Zhou*, H.-H. Wu*, J. Zhou, Stereoselective defluorinative carboxylation of gem-difluoroalkenes with carbon dioxideOrg. Chem. Front. 20196, 3678-3682.

Graphical abstract:Stereoselective defluorinative carboxylation of gem-difluoroalkenes with carbon dioxide

21.      P.-W. Xu,C. Chen,J.-K. Liu,Y.-T. Song,F. Zhou*, J. Yan*, J. Zhou*, One-Pot Sequential [3 + 3] Dipolar Cycloaddition of Aldehyde or Ketone and Hydroxylamine with Spirocyclopropyl OxindoleJ. Org. Chem.201883, 1276312774.

22.    P.-G. Ding, X.-S. Hu,F. Zhou*, J. Zhou*, Catalytic enantioselective synthesis of α-chiral azidesOrg. Chem. Front.20185, 1542-1559.

Graphical abstract:Catalytic enantioselective synthesis of α-chiral azides

23.       X.-T. Gao, C.-C. Gan, S.-Y. Liu, F. Zhou*, H.-H. Wu*, J. Zhou*, Utilization of CO2 as a C1 Building Block in a Tandem Asymmetric A3 Coupling-Carboxylative Cyclization Sequence to 2‑OxazolidinonesACS Catal.2017, 7, 8588-8593.

24.     F. Zhou*, S.-L. Xie, X.-T. Gao, R. Zhang,* C.-H. Wang, G.-Q. Yin, J. Zhou* Activation of (salen)CoI complex by phosphorene for carbon dioxide transformation at ambient temperature and pressureGreen Chem.201719, 3908-3915.

Graphical abstract:Activation of (salen)CoI complex by phosphorane for carbon dioxide transformation at ambient temperature and pressure

25.     J.-S. Yu, W.-B. Wu, F. Zhou*, The first catalytic asymmetric thioacetalization by chiral phosphoric acid catalysisOrg. Biomol. Chem.2016, 14, 2205-2209.

26.      K. Liao, F. Zhou*, J.-S. Yu, W.-M. Gao, J. Zhou, Catalytic asymmetric sulfenylation to structurally diverse dithioketalsChem. Commun.201551, 16255-16258.

Graphical abstract:Catalytic asymmetric sulfenylation to structurally diverse dithioketals

27.     Z.-Y. Cao, W. D. G. Brittain, J. S. Fossey, F. ZhouRecent advances in the use of chiral metal complexes with achiral ligands for application in asymmetric catalysisCatal. Sci. Technol. 20155, 3441-3451

Graphical abstract:Recent advances in the use of chiral metal complexes with achiral ligands for application in asymmetric catalysis

研究生期间发表论文

28.       F. Zhou, F.-M. Liao, J.-S. Yu, J. Zhou,* Catalytic Asymmetric Electrophilic Amination Reactions To Form Nitrogen-Bearing Tetrasubstituted Carbon StereocentersSynthesis201446, 2983-3003.

29.       F. Zhou, C. Tan, J. Tang, Y.-Y. Zhang, W.-M. Gao, H.-H. Wu, Y.-H. Yu and J. Zhou,*Asymmetric Copper(I)-Catalyzed Azide–Alkyne Cycloaddition to Quaternary Oxindoles. J. Am. Chem. Soc2013‚ 135‚ 10994-10997

30.      F. Zhou, X.-P. Zeng, C. Wang, X.-L. Zhao and J. Zhou*. Organocatalytic asymmetric synthesis of 3,3-disubstituted oxindoles featuring two heteroatoms at the C3 positionChem. Commun., 2013, 49, 2022.

Graphical abstract:Organocatalytic asymmetric synthesis of 3,3-disubstituted oxindoles featuring two heteroatoms at the C3 position

31.  F. Zhou‚ M. Ding‚ J. Zhou,*A Catalytic Metal-free Ritter Reaction to 3-Substituted 3-AminooxindolesOrg. Biomol. Chem.2012‚ 10‚ 3178-3183.

Graphical abstract:A catalytic metal-free Ritter reaction to 3-substituted 3-aminooxindoles

32.           F. Zhou‚ Z.-Y. Cao‚ J. Zhang‚ H. B. Yang‚ J. Zhou,*A Highly Efficient FriedelCrafts Reaction of 3-Hydroxyoxindoles and Aromatic Compounds to 33-Diaryl and 3-Alkyl-3-aryloxindoles Catalyzed by Hg(ClO4)23H2O. Chem. Asian J. 2012‚ 7 233-241.

Description unavailable

33.           F. Zhou‚ M. Ding‚ Y.-L. Liu‚ C.-H. Wang‚ C.-B. Ji‚ Y.-Y. Zhang, J. Zhou,*Organocatalytic Asymmetric α-Amination of Unprotected 3-Aryl and 3-Aliphatic Substituted Oxindoles using Di-tert-butyl Azodicarboxylate Adv. Syn. Catal. 2011‚ 353‚ 2945-2952.

Description unavailable

34.           F. Zhou‚ Y.-L. Liu‚ J. Zhou‚*Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 PositionAdv. Syn. Catal. 2010‚ 352‚ 1381-1407.

Description unavailable

35.           Z.-Y. Cao, F. Zhou, Y.-H. Yu, J. Zhou,*A Highly Diastereo- and Enantioselective Hg(II)-Catalyzed Cyclopropanation of Diazooxindoles and Alkenes Org. Lett.2013‚ 15, 42-45.

36.           F. Zhu, F. Zhou, Z.-Y. Cao, C. Wang, Y.-X. Zhang, C.-H. Wang*, J. Zhou,*A Facile Method for the Synthesis of 3-Substituted 3-(Alkylthio)oxindoles or 3-Alkoxyoxindoles Synthesis201244, 3129-3144.

37.            J.-S. Yu, F. Zhou, Y.-L. Liu, J. Zhou*, Organocatalytic asymmetric Michael addition of unprotected 3-substituted oxindoles to 1,4-naphthoquinone. Beilstein. J. Org. Chem. 20128, 1360-1365.

38.           L. Chen‚ F. Zhou‚ T.-D. Shi‚ J. Zhou*,Metal-Free Tandem Friedel–Crafts/Lactonization Reaction to Benzofuranones Bearing a Quaternary Center at C3 Position J. Org. Chem. 2012‚ 77‚ 4354-4362.

39.           M. Ding‚ F. Zhou‚ Y.-L. Liu‚ C.-H. Wang‚ X.-L. Zhao‚ J. Zhou,* Cinchona alkaloid-based phosphoramide catalyzed highly enantioselective Michael addition of unprotected 3-substituted oxindoles to nitroolefinsChem. Sci. 2011‚ 2‚ 2035-2039.

40.            Y.-L. Liu‚ T.-D. Shi‚ F. Zhou‚ X.-L. Zhao‚ X. Wang‚* J. Zhou,*Organocatalytic Asymmetric Strecker Reaction of Di- and Trifluoromethyl Ketoimines. Remarkable Fluorine Effect Org. Lett. 2011‚ 13‚ 3826-3829.

41.           Y.-L. Liu‚ F. Zhou‚ J.-J. Cao‚ C.-B. Ji‚ M. Ding‚ J. Zhou,*A facile method for the synthesis of oxindole based quaternary α-aminonitriles via the Strecker reactionOrg. Biomol. Chem. 2010‚ 8‚ 3847-3850.

42.           J.-J. Cao‚ F. Zhou‚J. Zhou*Improving the Atom Efficiency of the Wittig Reaction by a “Waste as Catalyst/Co-catalyst” Strategy Angew. Chem. Int. Ed. 2010‚ 49‚ 4976-4980.

43.           M. Ding‚ F. Zhou‚ Z.-Q. Qian‚ J. Zhou‚*Organocatalytic Michael addition of unprotected 3-substituted oxindoles to nitroolefinsOrg. Biomol. Chem. 2010‚ 8‚ 2912-1914.

44.           Z.-Q. Qian‚ F. Zhou‚ T.-P. Du‚ M. Ding‚ B.-L. Wang‚ X.-L. Zhao‚ J. Zhou*Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindolesChem. Commun. 2009‚ 6753-6755.

 


荣誉及奖励

20166月,上海市优秀博士学位论文

20145月,上海市优秀毕业生

201312月,华东师范校长奖学金

201312月,博士研究生国家奖学金

201212月,华东师范大学校长奖学金一等奖

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