Jin-Sheng YU

09/2011-06/2016: Ph.D., Shanghai Key Laboratory of Green Chemistry and Chemical Process, East China Normal University, Shanghai, China (With Prof. Jian Zhou).

02/2019-present: Research Professor, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, East China Normal University (ECNU), Shanghai, China.

01/2017-01/2019: JSPS Post-doctoral fellow, Institute of Microbial Chemistry, Tokyo, Japan (With Prof. Dr. Masakatsu SHIBASAKI, and Dr. Hidetoshi NODA).

07/2016-01/2017: Senior researcher, WuXi AppTec, Shanghai, China.

Selected publications：

17. Y.-J. Hao, X.-S. Hu, Y. Zhou*, J. Zhou, J.-S. Yu*, Catalytic Enantioselective α-Arylation of Carbonyl Enolates and Related Compounds. ACS Catal. 2020, 10, 955-993.

16. X.-S. Hu, J.-S. Yu*, J. Zhou*, Catalytic selective mono- and difluoroalkylation using fluorinated silyl enol ethers. Chem. Commun. 2019, 55, 13638-13648.

15. X.-S. Hu, P.-G. Ding, J.-S. Yu*, J. Zhou*, A Sc(OTf)3 catalyzed Mukaiyama-Mannich reaction of difluoroenoxysilanes with unactivated ketimines. Org. Chem. Front. 2019, 6, 2500-2505.

14. Y.-P. Tian, Y. Gong, Hu, X.-S. Hu, J.-S. Yu*, Y. Zhou*, J. Zhou*, HClO4 catalysed aldol-type reaction of fluorinated silyl enol ethers with acetals or ketals toward fluoroalkyl ethers. Org. Biomol. Chem. 2019, 17, 9430-9434.

13. K. Liao, X.-S. Hu, R.-Y. Zhu, R.‐H. Rao, J.-S. Yu*, F. Zhou, J. Zhou*, Catalytic Enantioselective Protonation of Monofluorinated Silyl Enol Ethers towards Chiral α-Fluoroketones. Chin. J. Chem. 2019, 37, 799-806. (Feature article)

12. P.-W. Xu, J.-S. Yu*, C. Chen, Z.-Y. Cao, F. Zhou, J. Zhou*, Catalytic Enantioselective Construction of Spiro Quaternary Carbon Stereocenters. ACS Catal. 2019, 9, 1820-1882.

11. Y. Gong, J.-S. Yu*, Y.-J. Hao, Y. Zhou*, J. Zhou*, Catalytic Enantioselective Aldol-Type Reaction Using alpha-Fluorinated Enolates. Asian J. Org. Chem. 2019, 8, 610-626.

10. J.-S. Yu, M. Espinosa, H. Noda*, M. Shibasaki*, Traceless Electrophilic Amination for the Synthesis of Unprotected Cyclic β‑Amino Acids. J. Am. Chem. Soc. 2019, 141, 10530-10537. (Highlighted bySynfacts 2019, 1072)

9. J.-S. Yu, H. Noda, N. Kumagai*, M. Shibasaki*, Direct Catalytic Asymmetric Mannich-Type Reaction of an α-CF3 Amide to Isatin Imines. Synlett, 2019, 30, 488-492. (Invited paper as part of the 30 Years SYNLETT-Pearl Anniversary Issue)

8. J.-S. Yu, H. Noda*, M. Shibasaki*, Quaternary β2,2-Amino Acids: Catalytic Asymmetric Synthesis and Incorporation into Peptides by Fmoc-Based Solid-Phase Peptide Synthesis. Angew. Chem. Int. Ed. 2018, 57, 818-822.

7. J.-S. Yu, H. Noda*, M. Shibasaki*, Exploiting β-Amino Acid Enolates in Direct Catalytic Diastereo- and Enantioselective C-C Bond-Forming Reactions. Chem. Eur. J. 2018, 24, 15796-15800.

6. J.-S. Yu, H.-M. Huang, P.-G. Ding, X.-S. Hu, F. Zhou, J. Zhou*, Catalytic Enantioselective Construction of Sulfur-containing Tetrasubstituted Carbon Stereocenters. ACS Catal. 2016, 6, 5139-5344.

5. J.-S. Yu, J. Zhou*, Organocatalytic Enantioselective Mukaiyama–Mannich Reaction of Fluorinated Enol Silyl Ethers and Cyclic N-Sulfonyl Ketimines. Org. Chem. Front. 2016, 3, 298-303.

4. J.-S. Yu, W.-B. Wu, F. Zhou*, The First Catalytic Asymmetric Thioacetalization by Chiral Phosphoric Acid Catalysis. Org. Biomol. Chem. 2016, 14, 2205-2209.

3. J.-S. Yu, F.-M. Liao, W.-M. Gao, K. Liao, J. Zhou*, Michael Addition Catalyzed by Chiral Secondary Amine Phosphoramide Using Fluorinated Silyl Enol Ethers: Formation of Quaternary Carbon Stereocenters. Angew. Chem. Int. Ed. 2015, 54, 7381-7385. (Highlighted by Synfacts 2015, 876)

2. J.-S. Yu, J. Zhou*, A Highly Efficient Mukaiyama–Mannich Reaction of N-Boc Isatin Ketimines and Other Active Cyclic Ketimines Using Difluoro Enol Silyl Ethers Catalyzed by Ph3PAuOTf. Org. Biomol. Chem. 2015, 13, 10968-10972. (Feature article)

1. J.-S. Yu, Y.-L. Liu, J. Tang, X. Wang*, J. Zhou*, Highly Efficient“On Water” Catalyst-free Nucleophilic Addition Reactions Using Difluoroenoxysilanes: Dramatic Fluorine Effects. Angew. Chem. Int. Ed. 2014‚53, 9512-9516. (被《有机化学》（2014, 34, 2184）作为亮点工作介绍)