About
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Professional Experience:
12/2016 – Full Professor Division of Organic Chemistry School of Chemistry and Molecular Engineering East China Normal University, Shanghai, China 07/2013 – 12/2016: Associate Professor Division of Organic Chemistry Department of Chemistry East China Normal University, Shanghai, China
09/2010 – 03/2013: Postdoctor in Organic Chemistry Advisor: Prof. Hong Wang Miami University, Oxford, OH, United States
Education: 09/2005 – 07/2010: Ph. D. in Organic Chemistry Department of Chemistry (Advisor: Prof. Junliang Zhang) East China Normal University, Shanghai, China
09/1997 – 06/2001: Bachelor in Chemistry Department of Chemistry Research FieldsWe focus on green organic synthesis. We developed new catalysts to achieve highly chemo-, regio- and enantio-selective organic reaction.We already pblished more than 20 SCI papres including Chem. Soc. Rev.(1), J. Am. Chem. Soc.(1), Angew. Chem. Int. Ed.(5)，Chem. Sci.（1）. 1）Highly selective C-H bond functionalization via diazo compounds
2）The development and application of novel multifuctional phosphine catalysts Enrollment and TrainingCourseScientificAcademic AchievementsPublications： 2019年 35.Zhenli Liu,Haofeng Xu（徐豪锋）, Tengfei Yao, Junliang Zhang*andLu Liu* Catalyst-Enabled Chemo-divergent Construction of Alkynyl and Vinyl Substituted Diarylmethanes Frompara-Quinone Methides and Alkynes. Org. Lett.,2019,21,7539-7543. https://pubs.acs.org/doi/10.1021/acs.orglett.9b02810
34.Zhunzhun Yu, Yongfeng Li, Peichao Zhang,Lu Liu* and Junliang Zhang* Ligand and counteranion enabled regiodivergentC–H bond functionalization of naphthols with aaryl-a-diazoesters.Chem. Sci.,2019,10, 6553–6559.
2018年
33. Yongfeng Li, Huamin Wang, Yuwei Su (苏雨薇),Runchen Li (李润尘), Cao Li,Lu Liu* and Junliang Zhang* Phosphine-Catalyzed [3+2] Cycloaddition reaction ofα-Diazoacetates andβ-Trifluoromethyl Enones: A Facile Access to Multisubstituted 4-CF3 Pyrazolines.Org. Lett.2018,20, 6444-6448.
32. Tao Zhou,Tong Xia (夏童), Zhenli Liu,Lu Liu* and Junliang Zhang* Asymmetric Phosphine‐Catalyzed [4 + 1] Annulations of o‐Quinone Methides with MBH Carbonates.Adv. Synth. Catal. 2018,360, 4475-4479.
31. Ben Ma,Lu Liu* and Junliang Zhang* Gold‐catalyzed Site‐selective C−H Bond Functionalization with Diazo Compounds.Asian J. Org. Chem. 2018, 7,2015-2025.
2017年
30. Chaoqian Huang, Yu Zeng, Huayu Cheng, Anjing Hu,Lu Liu,Yuanjing Xiao* and Junliang Zhang* A One-Pot Construction of Halogenated Trifluoromethylated Pyrroles through NXS (X = Br, I) Triggered Cascade.Org. Lett.2017, 19, 4968-4971. 29. Ben Huang, Cao Li, Huamin Wang,Caihui Wang (王才慧),Lu Liu* and Junliang Zhang* Phosphine-Catalyzed Diastereo- and Enantioselective Michael Addition of β-Carbonyl Esters to β-Trifluoromethyl and β-Ester Enones: Enhanced Reactivity by Inorganic Base.Org. Lett.2017, 19, 5102-5105.
28. Yu Zeng, Chaoqian Huang, Peiyun Ni,Lu Liu,Yuanjing Xiao* and Junliang Zhang* Silver-Catalyzed Double Hydrocarbonation of 2-Trifluoromethyl-1,3-Conjugated Enynes with 1,3-Dicarbonyl Compounds: Synthesis of Ring-Trifluoromethylated Cyclopentene.Adv. Synth. Catal.2017, 359, 3555-3559. 27. Ben Ma, Jiaojiao Wu (武娇娇),Lu Liu* and Junliang Zhang* Gold-catalyzedpara-selective C-H bond alkylation of benzene derivatives with donor/acceptor-substituted diazo compounds.Chem. Commun,2017, 53, 10164-10167.
（Highlighted by Organic Chemistry Portal）
26. Tao Zhou, Shenhuan Li, Ben Huang, Cao Li,Yang Zhao (赵阳), Jieqiong Chen, Aoling Chen, Yuanjing Xiao,Lu Liu* and Junliang Zhang* Phosphine-Catalyzed Friedel-Crafts Reaction of Naphthols withpara-Quinone Methides: An Expedient Access to Triarylmethanes.Org. Biomol. Chem. 2017,15, 4941-4945.
25. Shenhuan Li,‡Yuanyuan Liu,‡Ben Huang,Tao Zhou,Hongmei Tao (陶红梅), Yuanjing Xiao,Lu Liu* and Junliang Zhang* Phosphine-Catalyzed Asymmetric Intermolecular Cross Vinylogous Rauhut-Currier Reactions of Vinyl Ketones withpara-Quinone Methides.ACS Catal.2017,7,2805-2809. ‡ These authors contributed equally to this work
24.Lu Liu* and Junliang Zhang* The Development of Transition-Metal-Catalyzed C(sp2)-H Function-alization of Arenes with Diazo Compounds.Chin. J. Org. Chem.2017, 37, 1117-1126. (Invited review)
23.Ben Ma, Zhaowei Chu, Ben Huang, Zhenli Liu, Lu Liu* and Junliang Zhang* Highly para-selective C-H Alkylation of Benzene Derivatives with 2,2,2-Trifluoroethyl α-Aryl-α-diazoesters. Angew. Chem. Int. Ed., 2017, 56, 2749-2753.
22.Zhunzhun Yu,Yongfeng Li, Jiameng Shi, Ben Ma, Lu Liu and Junliang Zhang* (C6F5)3B -Catalyzed Highly Chemoselective and Ortho-selective C-H Bond Functionalization of Phenols Oriented by Hydrogen Bonds. Angew. Chem. Int. Ed., 2016, 55, 14807-14811.
21. Zhenting Yue, Wenbo Li, Lu Liu, Cuihong Wang* and Junliang Zhang* Enantioselective Synthesis of 4H-Pyrans Through Organocatalytic Asymmetric Formal [3+3] Cycloadditions of 2-(1-Alkynyl)-2-alken-1-ones with β-Keto Esters. Adv. Synth. Catal. 2016, 358, 3015-3020 (VIP). 20.Ben Ma, Ziang Wu, Ben Huang, Lu Liu* and Junliang Zhang* Gold-catalysed facile access to indene scaffold via sequential C-H functionalization and 5-endo-dig carbocyclization. Chem. Commun, 2016, 52, 9351-9354.
19. ZhunZhun Yu, Lu Liu* and Junliang Zhang* Triflic Acid-Catalyzed Enynes Cyclization: A New Strategy beyond Electrophilic π-Activation. Chem. Eur. J., 2016, DOI: 10.1002/chem.201601599
18. Haoxiang Hu, Yidong Wang, Deyun Qian, Zhan-Ming Zhang, Lu Liu* and Junliang Zhang* Enantioselective gold-catalyzed intermolecular [2 + 2]-cycloadditions of 3-styrylindoles with N-allenyl oxazolidinone. Org. Chem. Front., 2016, DOI: 10.1039/C6QO00087H
17. Yuan Liu, Zhunzhun Yu, Zhoujie Luo, John Zenghui Zhang, Lu Liu* and Fei Xia* Mechanistic Investigation of Aromatic C(sp2)-H and Alkyl C(sp3)-H Bond Insertion by Gold Carbenes. J. Phys. Chem. A 2016, 120, 1925-1932. http://pubs.acs.org/doi/abs/10.1021/acs.jpca.6b00636
16. Lu Liu* and Junliang Zhang* Gold-catalyzed transformations of α-diazocarbonyl compounds: selectivity and diversity. Chem. Soc. Rev. 2016, 45, 506-516. http://pubs.rsc.org/en/content/articlelanding/2015/cs/c5cs00821b#!divAbstract
15. Zhunzhun Yu, Haile Qiu, Lu Liu* and Junliang Zhang* Gold-Catalyzed Construction of Two Adjacent Quaternary Stereocenters via Sequential C-H Functionalization and Aldol Annulation. Chem. Commun. 2016, 52, 2257-2260. http://pubs.rsc.org/en/content/articlelanding/2015/cc/c5cc08880a#!divAbstract
14. Yuan Liu,‡ Zhunzhun Yu,‡ John Zenghui Zhang, Lu Liu,* Fei Xia* and Junliang Zhang* Origins of Unique Gold-Catalyzed Chemo- and Site-Selective C-H Functionalization of Phenols with Diazo Compounds. Chem. Sci. 2016,7, 1988-1995. http://pubs.rsc.org/en/content/articlelanding/2015/sc/c5sc04319k#!divAbstract ‡ These authors contributed equally to this work
2014年 13. Lu Liu and Junliang Zhang* Product Selectivity Control in the Domino Cyclization of 2-(2-Alkynylarylidene)-1,3-dicarbonyl Compounds Catalyzed by Metal Lewis Acids. Synthesis 2014, 46, 2133-2142. (Invited feature article) https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0034-1378392
12. Lai Wei, Lu Liu* and Junliang Zhang* Scandium-Catalyzed Tandem Selective Oxirane Ring-opening / Friedel-Crafts Alkylation: A Facile Access to [1,4]Oxazino[4,3-a]indoles and 3,4-Dihydro-1H-pyrrolo[2,1-c][1,4]oxazines. Org. Biomol. Chem. 2014, 12, 6869-6877. http://pubs.rsc.org/en/content/articlelanding/2014/ob/c4ob01057d#!divAbstract 11.Zhunzhun Yu, Ben Ma, Mingjin Chen, Hai-Hong Wu,Lu Liu*and Junliang Zhang* Highly Site-selective Direct C-H Bond Functionalization of Phenols with α-Aryl-α-Diazoacetates and Diazooxindoles via Gold Catalysis.J. Am. Chem. Soc.2014, 136,DOI:10.1021/ja503163k. (Featured in JACS Spotlights)http://pubs.acs.org/doi/abs/10.1021/ja503163k
10.Lu Liu, Philias Daka, Ryan Sarkisian, Yongming Deng, Kraig Wheeler, Hong Wang* Oxa-Diels-Alder Reaction of Isatins and Acyclic α,β-Unsaturated Methyl Ketones through Cooperative Dienamine and Metal Lewis Acid Catalysis. Synthesis 2014, 46, 1339-1347.
9.Lu Liu, Yongming Deng,Ryan Sarkisian, Hong Wang* Sc(OTf)3‑Catalyzed Three-Component Cyclization of Arylamines, β,γ-Unsaturated α‑Ketoesters, and 1,3-Dicarbonyl Compounds for the Synthesis of Highly Substituted 1,4-Dihydropyridines and Tetrahydropyridines. J. Org. Chem.2013, 78, 5751-5755. 8.Yongming Deng, Lu Liu, Ryan Sarkisian, Kraig Wheeler, Hong Wang,* Zhenghu Xu* Arylamine-Catalyzed Enamine Formation: Cooperative Catalysis with Arylamines and Acids. Angew. Chem. Int. Ed. 2013, 52, 3663-3667. (本文被Synfacts收录Synfacts,2013: 631.)
7.Lu Liu, Ryan Sarkisian, Zhenghu Xu, Hong Wang* Asymmetric Michael Addition of Ketones to Alkylidene Malonates and Allylidene Malonates via Enamine–Metal Lewis Acid Bifunctional Catalysis. J. Org. Chem.2012, 77, 7693-7699.
6.Zhenghu Xu, Lu Liu, Kraig Wheeler, Hong Wang* Asymmetric Inverse-Electron-Demand Hetero-Diels–Alder Reaction of Six-membered Cyclic Ketones: An Enamine/Metal Lewis Acid Bifunctional Approach. Angew. Chem. Int. Ed.2011, 50, 3484-3488. (本文被编辑选为 "Hot Paper" 同时被Synfacts收录Synfacts,2011: 747.)
5.Lu Liu, Lai Wei, Yong Lu, Junliang Zhang* One-Pot Tandem Catalysis: A Concise Route to Fused Bicyclic Scaffolds from Acyclic β-Ketoesters and Alkynyl Aldehydes. Chem.-Eur. J.2010, 16, 11813-11817.
4.Lu Liu, Lai Wei, Junliang Zhang* A Facile Route to Polysubstituted Naphthalenes and Benzofluorenols via Scandium Triflate- and Triflic Acid- Catalyzed Benzannulation of 2-(2-Alkynylarylidene)- 1,3-Dicarbonyl Compounds.Adv. Synth. Catal.2010, 352, 1920-1924.
3.Lu Liu, Junliang Zhang* Selectivity Control in Lewis Acid Catalyzed Regiodivergent TandemCationic Cyclization/Ring Expansion Terminated by PinacolRearrangement. Angew. Chem. Int. Ed.2009, 48, 6093-6096.
2.Ye Liu*, Lu Liu, Yong Lu, Yue-Qin Cai An imidazolium tosylate salt as efficient and recyclable catalystfor acetylation in an ionic liquid. Monatsh. Chem. 2008, 139, 633. 1.Lu Liu, Ye Liu*, Yue-Qin Cai Acetylation Catalyzed by Fuctionalized Ionic Liquid [bmim]OTs. 催化学报2008, 29, 341. Honor |
