姜丽琴

研究方向为：1）多组分新反应及其选择性调控的研究。通过捕捉活泼中间体发现多组分新反应并通过包括手性催化剂在内的多种催化剂实现其化学选择性和立体选择性的调控。2）多组分串联反应用于构建手性杂环化合物的研究。3)发展新试剂，设计新反应，如C-H 功能化新反应，烯烃双官能化新反应等，通过金属催化或金属催化与光催化共催化体系实现化学、位置、非对映、对映选择性的精准调控，原子经济型、高效、高选择性合成复杂功能分子。

培养学生：

   2018年甄龙同学获得国家奖学金。

   2022年刘赛楠同学获得国家奖学金。

近年学术成果如下：

24) Sainan Liu, Liqin jiang.*  Copper-Catalyzed Multicomponent Reactions of Intramolecular and Intermolecular Thiotrifluoromethylation of Alkenes: Access to CF3−Containing 2‑Iminothiazolidines and Isothioureas. Org. Lett. 2022, 24, 7157-7162.

23) Yaodi Shao, Zhi Yao, Junyi Zhou, Miao Yu, Suzhen Chen, Yanmei Yuan, Liu Han,* Liqin Jiang* and Junli Liu.* A novel small compound TOIDC suppresses lipogenesis via STEBP1-dependent signaling to curb MAFLD. Nutr. Metab. 2022, 19, Article number: 80. https://doi.org/10.1186/s12986-022-00713-0.

22) Miao Yu, Long Zhen, Liqin Jiang.* Cobalt-Catalyzed Hydrolysis/C-H Thiolation Cascade Reaction of N-Aryl Thiocarbamoyl Fluorides with Water: Access to 3-Alkyl-2(3H)-Benzothiazolones. Adv. Synth. Catal. 2022, 364, 3483-3488 (selected as "Very Important Publicacation (VIP)").

21) Zhongliang Cai, Junyi zhou, Miao Yu, Liqin jiang.* Ag-Catalyzed or Ag/PPh3-Catalyzed Chemoselective Switchable Cascade Reactions of N-Propargyl Thiocarbamoyl Fluorides and Malonate Esters. Org. Lett. 2022, 24, 293-298.

20) Zhongliang Cai, Zhi Yao, Liqin Jiang.* Pd-Catalyzed Coupling of Thioamides with N-Tosylhydrazones/ Trapping by Esters Cascade Reaction, Org. Lett. 2021, 23, 311-316.

19) Jun yang, Miao Yu, Liqin jiang.* Fe-catalyzed Dehydrogenative C-S Bond Formation for Access to 3-Alkyl-2-(N-aroyl)imino-benzo[d]thiazolines. Asian J. Org. Chem. 2021, 10, 3241-3244.

18) Zhi Yao, Zhongliang Cai, Long Zhen, Liqin Jiang.* Cobalt-Catalyzed Switchable Intramolecular Thioenolization/C−H Thiolation and C(sp2)−H/C(sp3)−H Dehydrogenative Coupling, Org. Lett. 2020, 22, 4505-4510.

17) Long Zhen, Hui Fan, Xiaoji Wang, Liqin Jiang.* Synthesis of thiocarbamoyl Fluorides and Isothiocyanates Using CF₃SiMe₃ and Elemental Sulfur or AgSCF₃ and KBr with Amines, Org. Lett. 2019, 21, 2106-2110.

16) Chenyun Zhang, Long Zhen, Zhi Yao, Liqin Jiang.* Iron(III)-Catalyzed Domino Claisen Rearrangement/Regio- and Chemoselective Aerobic Dehydrogenative Cyclization of β‑Naphthyl-Substituted-Allenylmethyl Ether, Org. Lett., 2019, 21, 955-959.

15) Jun Yang, Zhen long, Liqin Jiang.* Synthesis of N,N-Disubstituted Thiocarbamates from Thiocarbamoyl Fluorides with Alcohols/Phenols/Thiophenols/Thioalcohols Through Copper Catalysis, ChemistrySelect 2019, 4, 6177-6180.

14) Long Zhen, Kun Yuan, Xiuyan Li, Chenyun Zhang, Jun Yang, Hui Fan, Liqin Jiang.* Cascade Reaction of Propargyl Amines with AgSCF₃, as Well as One[1]-Pot Reaction of Propargyl Amines, AgSCF₃ and Di-tert-butyl Peroxide: Access to Allenyl Thiocyanates and Allenyl Triflfluoromethylthioethers, Org. Lett., 2018, 20, 3109-3113.    

13) Liqin Jiang, Weifeng Jin, Wenhao Hu.* Double C−H Functionalization of Indoles via Three-Component Reactions/CuCl₂‑Catalyzed Aerobic ehydrogenative Coupling for the Synthesis of Polyfunctional Cyclopenta[b]indoles, ACS Catal. 2016, 6, 6146−6150.

12) Liqin Jiang,* Renqi Xu, ZhenghuiKang, Yixiao Feng, Fengxia Sun, Wenhao Hu,* Rh(II)/Brønsted Acid Cocatalyzed Intramolecular Trapping of Ammonium Ylides with Enones: Diastereoselective Synthesis of 2,2,3-Trisubstituted Indolines, J. Org. Chem. 2014, 79, 8440-8446.

11) Liqin Jiang,* Copper/N,N-Dimethylglycine Catalyzed Goldberg Reactions Between Aryl Bromides and Amides, Aryl Iodides and Secondary Acyclic Amides, Molecules 2014, 19, 13448-13460.

10) Dan zhang, Huang Qiu, Liqin Jiang,* Fengping Lv, Chaoqiu Ma, Wenhao Hu,* Enantioselective Palladium(II) Phosphate Catalyzed Three-Component Reactions of Pyrrole, Diazoesters, and Imines, Angew. Chem. Int. Ed., 2013, 52, 13356-13360.

9) Liqin Jiang, Dan Zhang, Zhongqing Wang, Wenhao Hu,* Highly Enantioselective Three-Component Reactions of tert-Butyl Diazoacetate with Arylamines and Imines: An Efficient Synthesis of α,β-Bis(arylamino) Acid Derivatives, synthesis, 2013, 45, 0452-0458.

8) Huang Qiu, Ming Li, Li-Qin Jiang, Feng-Ping Lv,Li Zan, Chang-Wei Zhai, Michael P. Doyle, Wen-Hao Hu*, Highly enantioselective trapping of zwitterionic intermediates by imines, Nature Chemistry, 2012, 4, 733-738.

7) Jingjing Ji, Xia Zhang, Liqing Jiang, Wenhao Hu.* Tetrahedron Lett. 2012, 53, 182.

6) Ying-Guang Zhu, Hong-Zhu Kan, Li-Qin Jiang, Wen-Hao Hu.* syn. Commu. 2012, 42, 1137.

5) Xin chun Han, Minghua Gan, Huang Qiu, Jingjing Ji, Xia Zhang, Liqin Jiang,* Wenhao Hu.* Trapping of Oxonium Ylides with Michael Acceptors: Highly Diastereoselective Three-Component Reactions of Diazo Compounds with Alcohols and Benzylidene Meldrum’s Acids/4-Oxo-enoates, synlett., 2011, 1717-1722.

4) Xingchun Han,Liqing Jiang, Min Tang, Wenhao Hu.* Org. Biomol. Chem., 2011, 9, 3839

3) Jun Jiang, Hua-Dong Xu, Jian-Bei Xi, Bai-Yan Ren, Feng-Ping Lv, Xin Guo, Li-Qin Jiang, Zhi-Yong Zhang, Wen-Hao Hu.* J. Am. Chem. Soc. 2011, 133, 8428.

2) Yu Qian, Xinfang Xu, Liqin Jiang, Dipak Prajapati, Wenhao Hu.*J. Org. Chem., 2009, 74 (12), 4542.

1) Liqin Jiang, Xu Lu, Hui Zhang, Yongwen Jiang, Dawei Ma.* CuI/4-Hydro-L-proline as a More Effective Catalytic System for Coupling of Aryl Bromides with N-Boc Hydrazine and Aqueous Ammonia, J. Org. Chem., 2009, 74 (12), 4542-4546.