Kai Hong

2008.09-2015.02   Ph.D.     Boston College, Boston, MA, US (Advisor: Professor James P. Morken)

2004.09-2008.06   B.S.       University of Science and Technology of China, Hefei, Anhui, China

2015.03-2019.04      Postdoc，The Scripps Research Institute, La Jolla, CA, US 

                                 (Advisor: Professor Jin-Quan Yu)

2019.05-present       Professor, East China Normal University, Shanghai, China

10. Xie, X.-Y.; Wei, Y.; Chen, X.-Y.; Li, M.; Hong, K.* Palladium-Catalyzed gem-Diborylalkylation of Silyl Enol Ethers and N-Vinylacetamide via Diboryl Carbon-Centered Radicals. Adv. Sci. 2025, DOI: 10.1002/advs.202508566.

9. Wei, Y.; Hong, K.* Synthesis and Application of Geminal Halodiborylalkanes: Recent Advances and Future Perspectives. ChemCatChem 2025, DOI:10.1002/cctc.202500708. (Invited Review)

8. Gu, H.-Y.; Chen, X.-Y.; Yang, Y.-F.; Hong, K.* Diastereoselective Synthesis of Boryl-Substituted Vinylcyclopropanes via Deborylative Cyclization of Geminal Diboron Compounds. Org. Lett. 2025, DOI: 10.1021/acs.orglett.5c00886.

7. Xu, S.; Ning, P.-F.; Wei, Y.; Li, M.; Hong, K.* Synthesis of gem-Diborylcyclopropyl Ketones via Conjugate Addition of Chlorodiborylmethane to α,β-Unsaturated Ketones. Org. Lett. 2025, DOI: 10.1021/acs.orglett.5c00638.

6. Li, M.; Wei, Y.; Chen, D.; Ning, P.-F.; Yang, Y.-F.; Xie, X.-Y.; Liu, C.,* Hong, K.* Construction of 1,3-Diboryl Allenes from gem-Iododiboron Compounds via Intermolecular Boryl Group Transfer. Chin. J. Chem. 2025, 43, 949-955.

5. Yang, Y.-F.; Ning, P.-F.; Zhang, B.; Li, M.; Xie, X.-Y.; Hong, K.* Modular Synthesis of Geminal Iododiboron Compounds via Alkylation of Chlorodiborylmethane. Org. Lett. 2024, 26, 10285.

4. Wei, Y.;# Xie, X.-Y.;# Liu, J.; Liu, X.; Zhang, B.; Chen, X.-Y.; Li, S.-J.;* Lan, Y.; Hong, K.* Palladium-Catalyzed Cascade Heck Coupling and Allylboration of Iododiboron Compounds via Diboryl Radicals. Angew. Chem. Int. Ed. 2024, 63, e202401050 (# equal contribution)

* Highlighted by 化学加, 化学深耕堂

3. Ning, P.-F.;# Wei, Y.;# Chen, X.-Y.; Yang, Y.-F.; Gao, F.-C.; Hong, K.* A General Method to Access Sterically Encumbered Geminal Bis(boronates) via Formal Umpolung Transformation of Terminal Diboron Compounds. Angew. Chem. Int. Ed. 2024, 63, e202315232. (# equal contribution)

* Highlighted by X-MOL, Organic Chemistry Portal

2. Gao, F.-C.;# Li, M.;# Gu, H.-Y.; Chen, X.-Y.; Xu, S.; Wei, Y.; Hong, K.* Construction of α-Halogenated Boronic Esters via Visible Light-Induced C–H Bromination. J. Org. Chem. 2023, 88, 14246. (# equal contribution)

* Highlighted by Organic Chemistry Portal

1. Chen, X.-Y.;# Gao, F.-C.;# Ning, P.-F.; Wei, Y.; Hong, K.* Facile Access to Cyclopropylboronates via Stereospecific Deborylative Cyclization: A Leaving Group-Assisted Activation of Geminal Diborons. Angew. Chem. Int. Ed. 2023, 62, e202302638. (# equal contribution)

* Highlighted by Organic Chemistry Portal, X-MOL

Representative Publications Before ECNU:

6. Hong, K.; Park, H.; Yu, J.-Q.* Methylene C(sp³)‒H Arylation of Aliphatic Ketones Using a Transient Directing Group. ACS Catal. 2017, 7, 6938.

5. Zhang, F.-L.;^# Hong, K.;^# Li, T.-J.;^# Park, H.; Yu, J.-Q.* Functionalization of C(sp³)–H Bonds Using a Transient Directing Group. Science 2016, 351, 252. (^#equal contribution)

4. Hong, K.; Liu, X.; Morken, J. P.* Simple Access to Elusive a-Boryl Carbanions and Their Alkylation: An Umpolung Construction for Organic Synthesis. J. Am. Chem. Soc. 2014, 136, 10581.

3. Hong, K.; Morken, J. P.* Catalytic Enantioselective One-pot Aminoborylation of Aldehydes: A Strategy for Construction of Nonracemic a-Aminoboronates. J. Am. Chem. Soc. 2013, 135, 9252.

2. Ferris, G. E.; Hong, K.; Roundtree, I. A.; Morken, J. P.* A Catalytic Enantioselective Tandem Allylation Strategy for Rapid Terpene Construction: Application to the Synthesis of Pumilaside Aglycon. J. Am. Chem. Soc. 2013, 135, 2501.

1. Hong, K.; Morken, J. P.* Catalytic Enantioselective Diboration of Cyclic Dienes. A Modified Ligand with General Utility. J. Org. Chem. 2011, 76, 9102.