Defu He

1) Micro(nano)plastics pollution;

2) Solid waste and soil remendiation;

3) Toxicology research on emerging contaminants.

Dr. He finished his undergraduate study in HuNan Normal University in 1993. Then he worked in NanHua University as a teacher during from 1993 to 1998. He gained the Ph.D and became a faculty member at East China Normal University in 2003. From 2006 to 2007‚ he worked as postdoctoral fellowship at National Neuroscience Institute of Singapore. Then he has been working in East China Normal University.

Reviewer

Nature Communications · Environmental Science & Technology · Global Biology Change  ·  Journal of Hazardous Materials ·  Environment International · Science of the Total Environment · Environmental Pollution · Environmental Science: Nano · Scientific Reports · ES&T letters · Trends in Analytical Chemistry· Journal of Applied Toxicology · Environmental Science and Pollution Research · Ecotoxicology · Ecotoxicology and Environmental Safe · Neurotoxicity Research etc

1) Microplastics and Nanoplastics pollution;

2) Soil pollution and remendiation;

3) Toxicology on emerging contaminants.

(1) Environment and Health

(2) Environmental Physiology and Toxicology

My group is focusing on research work on (Micro)plastic pollution and the eco-environmental risks, the toxicity of emerging pollutants and its mechanisms.

1. Recently Selected Publications (*corresponding author):

[1]     Liang Y, Cao X, Mo A, Jiang J, Zhang Y, Gao W, He D*. Micro (nano) plastics in plant-derived food: Source, contamination pathways and human exposure risks. TrAC Trends in Analytical Chemistry, 2023, 117138.

[2]     Gao W, Mo A, Jiang J, Liang Y, Cao X, He D*. Removal of microplastics from water by coagulation of cationic-modified starch: An environmentally friendly solution. Science of The Total Environment, 2023, 166787

[3]     Cao X, Liang Y, Jiang J, Mo A, He D*. Organic additives in agricultural plastics and their impacts on soil ecosystems: Compared with conventional and biodegradable plastics. TrAC Trends in Analytical Chemistry, 2023, 117212.

[4]     Lv W, Gu H, He D, Liu Z, Yao C, Huang W, Yuan Q, Zhou W. Polystyrene nanospheres-induced hepatotoxicity in swamp eel (Monopterus albus): From biochemical, pathological and transcriptomic perspectives. Science of The Total Environment, 2023, 164844.

[5]     Li X, Chen Y, Gao W, Mo A, Zhang Y, Jiang J, He D*. Prominent toxicity of isocyanates and maleic anhydrides to Caenorhabditis elegans: Multilevel assay for typical organic additives of biodegradable plastics. Journal of hazardous materials, 2023, 442, 130051.

[6]     Mo A, Zhang Y, Gao W, Jiang J, He D*. Environmental fate and impacts of biodegradable plastics in agricultural soil ecosystems, Applied Soil Ecology, 2023, 181, 104667.

[7]     Tang R, Zhu D, Luo Y, He D, et al. Nanoplastics induce molecular toxicity in earthworm: Integrated multi-omics, morphological, and intestinal microorganism analyses. Journal of Hazardous Materials, 2023, 442, 130034.

[8]     Gao W, Zhang Y, Mo A, Jiang Jie, Liang Y, Cao X, He D*, Removal of microplastics in water: Technology progress and green strategies. Green Analytical Chemistry 2022, 3:100042.

[9]     Gao Z, Yu H, Li M, Li X, He D, Chen, Q. et al. A battery of baseline toxicity bioassays directed evaluation of plastic leachates—Towards the establishment of bioanalytical monitoring tools for plastics. Science of the Total Environment, 2022, 828, 154387

[10]   Chen Y, Li X, Gao W, Zhang Y, Mo A, Jiang J, He D*. Microfiber-loaded bacterial community in indoor fallout and air-conditioner filter dust. The Science of the total environment, 2022, 856, 159211.

[11]   Zhang Y, Gao W, Mo A, Jiang J, He D*. Degradation of polylactic acid/polybutylene adipate films in different ratios and the response of bacterial community in soil environments. Environmental pollution, 2022, 313, 120167.

[12]   Hu J, He D*, Zhang X, Li X, Chen Y, Gao W, Zhang Y, Ok YS, Luo Y. National-scale distribution of micro(meso)plastics in farmland soils across China: Implications for environmental impacts. Journal of Hazardous Materials, 2022, 424: 127283.

[13]   Zhang Y, Zhang X, Li X, He D*. Interaction of microplastics and soil animals in agricultural ecosystems. Current Opinion in Environmental Science & Health, 2022, 26: 100327.

[14]   Zhang X, Chen Y, Li X, Zhang Y, Gao W, Jiang J, Mo A, He D*. Size/shape-dependent migration of microplastics in agricultural soil under simulative and natural rainfall. Science of the Total Environment, 2022, 815: 152507.

[15]   Chen Y, Li X, Zhang X, Zhang Y, Gao W, Wang R, He D*. Air conditioner filters become sinks and sources of indoor microplastics fibers. Environmental Pollution, 2022, 292: 118465.

[16]   Shi X, Zhang X, Gao W, Zhang Y, He D*. Removal of microplastics from water by magnetic nano-Fe3O4. Science of The Total Environment, 2022, 802: 149838.

[17]   He D*, Zhang X, Hu J. Methods for separating microplastics from complex solid matrices: Comparative analysis. Journal of Hazardous Materials, 2021, 409: 124640.

[18]   He D*, Zhang Y, Gao W. Micro(nano)plastic contaminations from soils to plants: human food risks. Current Opinion in Food Science, 2021, 41: 116-121.

[19]   Li X, Hu J, Qiu R, Zhang X, Chen Y, He D*. Joint toxic effects of polystyrene nanoparticles and organochlorine pesticides (chlordane and hexachlorocyclohexane) on Caenorhabditis elegans. Environment Science: Nano, 2020, 7: 3062-3073

[20]   Song Y, Qiu R, Hu J, Li X, Zhang X, Chen Y, Wu WM*, He D*. Biodegradation and disintegration of expanded polystyrene by land snails Achatina fulica. Science of The Total Environment 2020, 746: 141289.

[21]   Chen Y, Ling Y, Li X, Hu J, Cao C, He D*. Size-dependent cellular internalization and effects of polystyrene microplastics in microalgae P. helgolandica var. tsingtaoensis and S. quadricauda. Journal of Hazardous Materials, 2020, 399: 123092.

[22]   Lu S, Qiu R, Hu J, Li X, Chen Y, Zhang X, Cao C, Shi H, Xie B, Wu WM*, He D*. Prevalence of microplastics in animal-based traditional medicinal materials: Widespread pollution in terrestrial environments. Science of the Total Environment, 2020: 709.

[23]   Liu M, Song Y, Lu S, Qiu R, Hu J, Li X, Bigalke M, Shi H, He D*. A method for extracting soil microplastics through circulation of sodium bromide solutions. Science of The Total Environment, 2019, 691: 341-347.

[24]   Song Y, Cao C, Qiu R, Hu J, Liu M, Lu S, Shi H, Raley-Susman KM, He D*. Uptake and adverse effects of polyethylene terephthalate microplastics fibers on terrestrial snails (Achatina fulica) after soil exposure. Environment Pollution, 2019, 250: 447-455. (Highly cited)

[25]   Lv W, Zhou W, Lu S, Huang W, Yuan Q, Tian M, Lv W*, He D*. Microplastic pollution in rice-fish co-culture system: A report of three farmland stations in Shanghai, China. Science of The Total Environment, 2019, 652: 1209-1218. (Highly cited)

[26]   He D*, Luo Y, Lu S, Liu M, Song Y, Lei L. Microplastics in soils: analytical methods, pollution characteristics and ecological risks. Trends in Analytical Chemistry, 2018, 109: 163-172. (Highly cited, Cover)

[27]   Lei L, Wu S, Lu S, Liu M, Song Y, Fu Z, Shi H, Raley-Susman KM, He D*. Microplastic particles cause intestinal damage and other adverse effects in zebrafish Danio rerio and nematode Caenorhabditis elegans. Science of The Total Environment, 2018a, 619-620: 1-8. (Highly cited)

[28]   Lei L, Liu M, Song Y, Lu S, Hu J, Cao C, Xie B, Shi H, He D*. Polystyrene (nano)microplastics cause size-dependent neurotoxicity, oxidative damages and other adverse effects in Caenorhabditis elegans. Environment Science: Nano, 2018b, 5: 2009-2020. (Highly cited)

[29]   Wu S, Lei L, Song Y, Liu M, Lu So, Lou D, Shi Y, Wang Z*, He D*. Mutation of hop-1 and pink-1 attenuates vulnerability of neurotoxicity in C. elegans: the role of mitochondria-associated membrane proteins in Parkinsonism. Experimental Neurology, 2018, 309: 67-78.

[30]   Liu M, Lu S, Song Y, Lei L, Hu J, Lv W, Zhou W, Cao C, Shi H, Yang X, He D*. Microplastic and mesoplastic pollution in farmland soils in suburbs of Shanghai, China. Environmental Pollution, 2018, 242: 855-862. (Highly cited)

[31]   Wu S, Lei L, Liu M, Song Y, Lu S, Li D, Shi H, Raley-Susman KM., He D*. Single and mixture toxicity of strobilurin and SDHI fungicides to Xenopus tropicalis embryos. Ecotoxicology and Environmental Safety. 2018. 153: 8-15.

[32]   Xu T, Zhang M, Hua J, Li Z, Wu T, Bao J, Wu S, Lei L, He D*. Behavioral deficits and neural damage of Caenorhabditis elegans induced by three rare earth elements. Chemosphere. 2017. 181: 55-62.

[33]   Xu T, Li P, Wu S, Lei L, He D*. Tris(2-chloroethyl) phosphate (TCEP) and tris(2-chloropropyl) phosphate (TCPP) induce locomotor deficits and dopaminergic degeneration in Caenorhabditis elegans. Toxicology Research. 2017, 6: 63-72.

[34]   Li P, Xu T, Wu S, Lei L, He D*. Chronic exposure to graphene-based nanomaterials induces behavioral deficits and neural damages in Caenorhabditis elegans. Journal of Applied Toxicology. 2017, 37(10): 1140-1150.

[35]   Li D, Liu M, Yang Y, Shi H, Zhou J, He D*. Strong lethality and teratogenicity of strobilurins on Xenepus tropicalis embryo: basing on ten agricultural fungicides. Environmental Pollution. 2016, 208: 868-874.

[36]   Xu T, Li P, Wu S, Li D, Wu J, Raley-Susman KM, He D*. Chronic exposure to perfluorooctane sulfonate reduces lifespan of Caenorhabditis elegans through insulin/IGF-1 signaling. Bulletin of Environmental Contamination and Toxicology. 2016, 97: 119-123.

[37]   Li J, Li D, Yang Y, Xu T, Li P, He D*. Acrylamide induces locomotor defects and degeneration of dopamine neurons in Caenorhabditis elegans. Journal of Applied Toxicology, 2016, 36: 60-67.

[38]   Zhu E, Chen N, Liu M, L Jia, L Dan, Yang Y, Zhang Y, He D*. Isomers and their metabolites of endosulfan induced cytotoxicity and oxidative damage in SH-SY5Ycells. Environmental Toxicology, 2016, 31(4): 496-504.

[39]   He D*, Chen R., Zhu E, et al. Toxicity bioassays for water from black-odor rivers in Wenzhou, China. Environmental Science and Pollution Research, 2015, 22(3): 1731-1741.

2. Recent Book