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周晓明

教授

生命科学学院      

导航

  • 个人资料
  • 研究方向
  • 招生与培养
  • 开授课程
  • 科研项目
  • 学术成果
  • 荣誉及奖励

个人资料

  • 部门： 生命科学学院
  • 毕业院校： 华东师范大学
  • 学位： 博士
  • 学历：
  • 邮编：
  • 联系电话： 021-62604169
  • 传真： 021-62233754
  • 电子邮箱： xmzhou@bio.ecnu.edu.cn
  • 办公地址： 华东师范大学脑功能基因组学教育部重点实验室
  • 通讯地址： 华东师范大学脑功能基因组学教育部重点实验室, 上海, 200062

教育经历

工作经历

个人简介

社会兼职

上海市生理科学会理事

上海市神经科学会理事

上海市医学会听觉与前庭委员会委员

江苏省发育生物学会听觉科学专业委员会特邀委员

中国生物物理学会听觉，语言和交流研究分会委员

中国听力医学发展基金会第五届专家指导委员会基础研究专家委员会委员

Auditory Cognitive Neuroscience, Review Editor, Member of the Editorial Board

研究方向

主要研究领域为感觉神经生物学。采用分子神经生物学、神经电生理学及行为学等技术和方法，以听觉系统为模型研究脑感觉认知及可塑性机制。研究获上海市青年科技启明星计划、启明星(跟踪)计划、浦江人才计划、上海市基础研究重点项目、教育部新世纪优秀人才计划及自然科学基金等资助。已发表研究论文60篇(其中作为第一或通讯作者的有2篇Nature子刊，5篇PNAS，4篇J Neurosci及4篇Cereb Cortex)并授权5项专利。成果获教育部高等学校科学技术奖(自然科学奖)二等奖(排名第一)及上海市科学技术奖励自然科学三等奖(排名第一)。


招生与培养

开授课程

科研项目

学术成果

Selected publications:


1. Cheng Y, Chen R, Su B, Zhang G, Sun Y, An P, Fang Y, Zhang Y, Shan Y, de Villers-Sidani É, Wang Y, Zhou X (2023) Pairing with enriched sound exposure restores auditory processing degraded by an antidepressant. J Neurosci 2023 MAR 15:JN-RM-2027-22. doi: 10.1523/JNEUROSCI.2027-22.2023.

 

2. Cheng Y, Tang B, Zhang G, An P, Sun Y, Gao M, Zhang Y, Shan Y, Zhang J, Liu Q, Lai CSW, de Villers-Sidani É, Wang Y, Zhou X (2022) Degraded cortical temporal processing in the valproic acid-induced rat model of autism. Neuropharmacology 209:109000


3. Zhang Y, Zhu M, Sun Y, Tang B, Zhang G, An P, Cheng Y, Shan Y, Merzenich MM, Zhou X (2021) Environmental noise degrades hippocampus-related learning and memory. Proc Natl Acad Sci USA 118(1):e2017841117

 

4. Cheng Y, Zhang Y, Wang F, Jia G, Zhou J, Shan Y, Sun X, Yu L, Merzenich MM, Recanzone G, Yang L, Zhou X (2020) Reversal of age-related changes in cortical sound-azimuth selectivity with training. Cereb Cortex 30:1768-1778

 

5. Liu X, Wei F, Cheng Y, Zhang Y, Jia G, Zhou J, Zhu M, Shan Y, Sun X, Yu L, Merzenich MM, Lurie D, Zheng Q, Zhou X (2019) Auditory training reverses lead (Pb)-toxicity-induced changes in sound-azimuth selecticity of cortical neurons. Cereb Cortex 29:3294-3304

 

6. Cheng Y, Jia G, Zhang Y, Hao H, Shan Y, Yu L, Sun X, Zheng Q, Kraus N, Merzenich MM, Zhou X (2017) Positive impacts of early auditory training on cortical processing at an older age. Proc Natl Acad Sci USA 114:6364-6369

 

7. Zhu X, Liu X, Wei F, Wang F, Merzenich MM, Schreiner CE, Sun X, Zhou X (2016) Perceptual training restores impaired cortical temporal processing due to lead exposure. Cereb Cortex 26:334-345

 

8. Zhou X, Lu YF, Darling RD, Simpson KL, Zhu X, Wang F, Yu L, Sun X, Merzenich MM, Lin RC (2015) Behavioral training reverses global cortical network dysfunction induced by perinatal antidepressant exposure. Proc Natl Acad Sci USA 112:2233-2238

 

9. Zhu X, Wang F, Hu H, Sun X, Kilgard MP, Merzenich MM, Zhou X (2014) Environmental acoustic enrichment promotes recovery from developmentally degraded auditory cortical processing. J Neurosci 34:5406-5415

 

10. Zhang Y, Zhao Y, Zhu X, Sun X, Zhou X (2013) Refining cortical representation of sound azimuths by auditory discrimination training. J Neurosci 33:9693-9698

 

11. Zhou X, Merzenich MM (2012) Environmental noise exposure degrades normal listening processes. Nat Commun 10.1038/ncomms1849, 3:843

 

12. Guo F, Zhang J, Zhu X, Cai R, Zhou X, Sun X (2012) Auditory discrimination training rescues developmentally degraded directional selectivity and restores mature expression of GABAA and AMPA receptor subunits in rat auditory cortex. Behav Brain Res 229:301-307

 

13. Zhou X, Panizzutti R, de Villers-Sidani É, Madeira C, Merzenich MM (2011) Natural restoration of critical period plasticity in the juvenile and adult primary auditory cortex. J Neurosci 31:5625-5634

 

14. Pan Y, Zhang J, Cai R, Zhou X, Sun X (2011) Developmentally degraded directional selectivity of the auditory cortex can be restored by auditory discrimination training in adults. Behav Brain Res 225:596-602

 

15. Zhou X, de Villers-Sidani É, Panizzutti R, Merzenich MM (2010) Successive-signal biasing for a learned sound sequence. Proc Natl Acad Sci USA 107:14839-14844

 

16. Cai R, Zhou X, Guo F, Xu J, Zhang J, Sun X (2010) Maintenance of enriched environment-induced changes of auditory spatial sensitivity and expression of GABA(A), NMDA, and AMPA receptor subunits in rat auditory cortex. Neurobiol Learn Mem 94:452-460

 

17. de Villers-Sidani É, Alzghoul L, Zhou X, Simpson KL, Lin RCS, Merzenich MM (2010) Recovery of age-related changes in the rat primary auditory cortex with operant training. Proc Natl Acad Sci USA 107:13900-13905

 

18. Zhou X, Merzenich MM (2009) Developmentally degraded cortical temporal processing restored by training. Nat Neurosci 12:26-28

 

19. Zhou X, Merzenich MM (2008) Enduring effects of early structured noise exposure on temporal modulation in the primary auditory cortex. Proc Natl Acad Sci USA 105:4423-4428

 

20. Zhou X, Nagarajan N, Mossop BJ, Merzenich MM (2008) Influences of un-modulated acoustic inputs on functional maturation and critical-period plasticity of the primary auditory cortex. Neuroscience 154:390-396

 

21. Zhou X, Merzenich MM (2007) Intensive training in adults refines A1 representations degraded in an early postnatal critical period. Proc Natl Acad Sci USA 104:15935-15940

 

22. Zhou X, Jen PH (2007) Corticofugal modulation of multi-parametric auditory selectivity in the midbrain of the big brown bat. J Neurophysiol 98:2509-2516

 

23. Zhou X, Jen PHS (2005) Corticofugal modulation of directional sensitivity in the midbrain of the big brown bat, Eptesicus fuscus.Hear Res 203:201-215

 

24. Jen PHS, Zhou X (2003) Corticofugal modulation of amplitude domain processing in the midbrain of the big brown bat, Eptesicus fuscus. Hear Res 184:91-106

 

25. Zhou X, Jen PHS (2002) The role of GABAergic inhibition in shaping directional selectivity of bat inferior collicular neurons determined with temporally patterned pulse trains. J Comp Physiol 188:815-826

 

26. Jen PHS, Zhou X, Zhang JP, Chen QC, Sun XD (2002) Brief and short-term corticofugal modulation of acoustic signal processing in the bat midbrain. Hear Res 168:196-207

 

27. Zhou X, Jen PHS (2002) The effect of sound duration on rate-intensity functions of inferior collicular neurons in the big brown bat, Eptesicus fuscus. Hear Res 166:124-135

 

28. Jen PHS, Zhou X, Wu CH (2001) Temporally patterned sound pulse trains affect intensity and frequency sensitivity of inferior collicular neurons of the big brown bat, Eptesicus fuscus. J Comp Physiol 187:605-616

 

29. Zhou X, Jen PHS (2001) The effect of sound intensity on duration tuning characteristics of bat inferior collicular neurons. J Comp Physiol 187:63-73

 

30. Zhou X, Jen PHS (2000) Brief and short-term corticofugal modulation of subcortical auditory responses in the big brown bat, Eptesicus fuscus. J Neurophysiol 84:3083-3087

 

31. Zhou X, Jen PHS (2000) Neural inhibition sharps spatial selectivity of bat inferior collicular neurons. J Comp Physiol 186:389-398

 

32. Jen PHS, Zhou X (1999) Temporally patterned sound trains affect duration tuning characteristics of bat inferior collicular neurons. J Comp Physiol 185:471-478


荣誉及奖励

10 访问

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