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张强

研究员

生命科学学院      

个人资料

  • 部门: 生命科学学院
  • 毕业院校: 中国科学技术大学
  • 学位: 博士
  • 学历: 博士研究生
  • 邮编: 200241
  • 联系电话: 021-54342622
  • 传真: 021-54342622
  • 电子邮箱: qzhang@bio.ecnu.edu.cn
  • 办公地址: 华东师范大学闵行校区生命科学学院451室
  • 通讯地址: 上海市东川路500号,华东师范大学生命科学学院451室,200241

教育经历

2008-2010  美国圣路易斯华盛顿大学    访问学者

2005-2011  中国科学技术大学        博士

2001-2005  中国科学技术大学        学士


工作经历

2018-至今   华东师范大学        研究员

2012-2013   美国佐治亚理工学院    博士后

2011-2017   华东师范大学        副研究员


个人简介

主要从事生物质纳米材料的绿色制备与高值化应用研究Cell, Sci. Adv., J. Am. Chem. Soc., Angew. Chem. Int. Ed., ACS Nano, Biomaterials等国际一流期刊上发表学术论文70余篇,多篇文章被评为ESI高被引论文,文章他引超过3000次,申请发明专利7,主持国家自然科学基金4项,省部级项目3项,企事业单位联合开发项目3项,获得上海市晨光计划、上海市浦江人才计划支持。


社会兼职

2019-至今 中国生物工程学会青年工作委员会委员

2016-至今 中国化学会会员

2016-至今 中国生物物理学会会员


研究方向

1. 生物质纳米材料的绿色制备

2. 生物质复合材料的制备及性能

3. 生物质纳米材料的高值化应用




招生与培养

开授课程

1.  多学科视角下的生命科学:前沿与思维

2. 现代生物学技术原理与应用


科研项目

学术成果

Cell, Sci. Adv., J. Am. Chem. Soc., Angew. Chem. Int. Ed., ACS Nano, Biomaterials等国际一流期刊上发表学术论文70余篇,多篇文章被评为ESI高被引论文,文章他引超过3000次,代表性论文如下(§第一作者,*通讯作者):


1.        L. Wang, W. Zhao, Y. Zhao, W. Li*, G. Wang*, Q. Zhang*Enzymatically-mineralized double-network hydrogels with ultrahigh mechanical strength, toughness, and stiffness. Theranostics 2023, 13, 673-684.

2.    S. Pan, Y. Li, X. Tong, L. Chen, L. Wang, T. Li*, Q. Zhang*, Strongly-adhesive easily-detachable carboxymethyl cellulose aerogel for noncompressible hemorrhage control. Carbohydrate Polymers 2023, 301, 120324.

3.    Y. Li, D. Wang, X. Ping, Y. Zhang, T. Zhang, L. Wang, L. Jin, W. Zhao, M. Guo, F. Shen, M. Meng, X. Chen, Y. Zheng, J. Wang, D. Li, Q. Zhang *, C. Hu*, L. Xu*, X. Ma*, Local hyperthermia therapy induces browning of white fat and treats obesity. Cell 2022, 185: 1-18.

4.    L. Wang,C. Zhang,W. Zhao, W. Li, G. Wang*X. Zhou*Q. Zhang*, Water-swellable cellulose nanofiber aerogel for control ofhemorrhage from penetrating wounds. ACS Applied Bio Materials 2022, 5, 10, 4886-4895.

5.    L. Wang, Y.T. Wang, W. Zhao, K.L. Lin, W. Li *, G.D. Wang*, Q. Zhang*, Library Screening to Identify Highly-Effective Autophagy Inhibitors for Improving Photothermal Cancer Therapy. Nano Letters 2021, 21, 9476-9484.

6.    L. Wang, Q. Cui, S. Pan, Y. Li, Y. Jin, H. Yang, T. Li*Q. Zhang*Facile isolation of cellulose nanofibers from soybean residue.Carbohydrate Polymer Technologies and Applications. 2021, 2, 100172.

7.    Y. Wang, H. Chen, K. Lin, T. Ying, Q. Huang, X. Cai, J. Xiao, Q. Zhang*, Y. Cheng*, Breaking the vicious cycle between tumor cell proliferation and bone resorption by chloroquine loaded and bone-targeted polydopamine nanoparticles. Science China Materials2021, 64, 474-487.

8.    Z. Zhou, Y. Yan, Q. Zhang*, Y. Cheng*, Melanin-likenanoparticles loaded with an angiotensin antagonist for an improvedphotothermal cancer therapy. Biomaterials Science, 2020, 8, 1658-1668.

9.    Y. Liu, H. Liu, L. Wang, Y. Wang, C. Zhang,C. Wang, Y. Yan, J. Fan, G. Xu*, Q. Zhang*, Amplification of oxidative stress via intracellularROS production and antioxidant consumption bytwo natural drug-encapsulated nanoagents forefficient anticancer therapy. Nanoscale Advances, 2020, 2, 3872-3881.

10.  Q. Zhang, L. Long, G. Zhang, Z. Li, Y. Zheng *, Seeded growth of silver nanoplates with rough edges and their applications for SERS, CrystEngComm, 2020, 22, 173-177.

11.  Z. Zhou, T. Fan, Y. Yan, S. Zhang, Y. Zhou, H. Deng, X. Cai, J. Xiao, D. Song, Q. Zhang*, Y. Cheng*, One stone with two birds: Phytic acid-capped platinum nanoparticles for targeted combination therapy of bone tumors. Biomaterials 2019, 194, 130-138.

12.  Z. Zhou, Y. Yan, L. Wang, Q. Zhang*, Y. Cheng*, Melanin-like nanoparticles decorated with an autophagy-inducing peptide for efficient targeted photothermal therapy. Biomaterials 2019, 203, 63-72.

13.  S. Zhang, C. Wang, H. Chang, Q. Zhang*, Y. Cheng* Off-on manipulation of enzyme activity by a near-infrared laser. Science Advances 2019, 5, eaaw4252.

14.  Y. Yan, X. Gao, S. Zhang, Y. Wang, Z. Zhou, J. Xiao, Q. Zhang*, Y. Cheng*, A carboxyl-terminated dendrimer enables osteolytic lesion targeting and photothermal ablation of malignant bone tumors. ACS Applied Materials & Interfaces 2019, 11, 160-168.

15.  C. Chang, C. Wang, C. Zhang, L. Li, Q. Zhang*Q. Huang*, Albumin-encapsulated platinum nanoparticles for targeted photothermal treatment of glioma.Journal of Biomedical Nanotechnology 2019,15, 1744-1753.

16.  Y. Wang, Q. Huang, X. He, H. Chen, Y. Zou, Y. Li, K. Lin, X. Cai, J. Xiao, Q. Zhang*, Y. Cheng*, Multifunctional melanin-like nanoparticles for bone-targeted chemophotothermal therapy of malignant bone tumors and osteolysis. Biomaterials 2018, 183, 10-19.

17.  X. Wang, C. Wang, X. Wang, Y. Wang, Q. Zhang*, Y. Cheng*, A polydopamine nanoparticle-knotted poly(ethylene glycol) hydrogel for on-demand drug delivery and chemo-photothermal therapy. Chemistry of Materials 2017, 29, 1370-1376.

18.  Y. Wang, J. Yang, H. Liu, X. Wang, Z. Zhou, Q. Huang, D. Song, X. Cai, L. Lin, K. Lin, J. Xiao, P. Liu, Q. Zhang*, Y. Cheng*, Osteotropic peptide-mediated bone targeting for photothermal treatment of bone tumors. Biomaterials 2017, 114, 97-105.

19.  C. Wang§, Q. Zhang§, X. Wang, H. Chang, S. Zhang, Y. Tang, J. Xu, R. Qi, Y. Cheng*, Dynamic modulation of enzyme activity by near-infrared light. Angewandte Chemie International Edition2017, 56, 1-7. 

20.  Z. Zhou, Y. Yang, K. Hu, Y. Zou, Y. Li, R. Ma, Q. Zhang*, Y. Cheng*, Autophagy inhibition enabled efficient photothermal therapy at a mild temperature. Biomaterials 2017, 141, 116-124.

21.  S. Wang§, F. Wang§, Q. Zhang*, Y. Cheng*, A core-shell structured polyplex for efficient and non-toxic gene delivery. Journal of Materials Chemistry B 2017, 5, 5101-5108. 

22.  Z. Zhou§, Y. Wang§, Y. Yan, Q. Zhang*, Y. Cheng*, Dendrimer-templated ultrasmall and multifunctional photothermal agents for efficient tumor ablation. ACS Nano 2016, 10, 4863-4872.

23.  Z. Zhou, K. Hu, R. Ma, Y. Yan, B. Ni, Y. Zhang, L. Wen, Q. Zhang*, Y Cheng*, Dendritic platinum-copper alloy nanoparticles as theranostic agents for multimodal imaging and combined chemo-photothermal therapy. Advanced Functional Materials 2016, 26, 5971-5978.

24.  X. Wang§, J. Zhang§, Y. Wang, C. Wang, J. Xiao*, Q. Zhang*, Y. Cheng*, Multi-responsive photothermal-chemotherapy with drug-loaded melanin-like nanoparticles for synergetic tumor ablation. Biomaterials 201681, 114-124.

25.  C. Wang, X. Wang, K. Dong, J. Luo, Q. Zhang*, Y. Cheng*, Injectable and responsively degradable hydrogel for personalized photothermal therapy. Biomaterials 2016, 104, 129-137.

26.  X. Wang, C. Wang, Q. Zhang*, Y. Cheng*, Near infrared light-responsive and injectable supramolecular hydrogels for on-demand drug delivery. Chemical Communications 2016, 52, 978-981.

27.  Y. Wang, M. Wang, H. Chen, H. Liu, Q. Zhang*, Y. Cheng*, Fluorinated dendrimer for TRAIL gene therapy in cancer treatment. Journal of Materials Chemistry B 2016, 4, 1354.

28.  J. Yang§, Q. Zhang§, H. Chang, Y. Cheng*, Surface-engineered dendrimers in gene delivery. Chemical Reviews 2015, 115, 5274-5300.

29.  C. Wang§, X. Cai§, J. Zhang, X. Wang, Y. Wang, H. Ge, W. Yan, Q. Huang, J. Xiao*, Q. Zhang*, Y. Cheng*, Trifolium-like platinum nanoparticle-mediated photothermal therapy inhibits tumor growth and osteolysis in a bone metastasis model. Small 2015, 11, 2080-2086.

30.  X. Wang, Y. Zhang, T. Li, W. Tian, Q. Zhang*, Y. Cheng*, Generation 9 polyamidoamine dendrimer encapsulated platinum nanoparticle mimics catalase size, shape, and catalytic activity. Langmuir 2013, 29, 5262–5270.

31.  Q. Zhang, Y. Yang, J. Li, R. Iurilli, S. Xie, D. Qin*, Citrate-free synthesis of Ag nanoplates and the mechanistic study. ACS Applied Materials & Interfaces 2013, 5, 6333-6345.

32.  Q. Zhang, C. Moran, X. Xia, M. Rycenga, N. Li, Y. Xia*, Synthesis of Ag nanobars in the presence of single-crystal seeds and a bromide compound, and their surface-enhanced Raman scattering Properties. Langmuir 2012, 28, 9047–9054.

33.  Q. Zhang, W. Li, L.-P. Wen, J. Chen, Y. Xia*, Facile synthesis of Ag nanocubes of 30 to 70 nm in edge length with CF3COOAg as a precursor. Chemistry-A European Journal 2010, 16, 10234-10239.

34.  Q. Zhang§, W. Li§, C. Moran, J. Chen, L.-P. Wen, Y. Xia*, Seed-mediated synthesis of Ag nanocubes with controllable edge lengths in the range of 30-200 nm and comparison of their optical properties. Journal of American Chemical Society 2010, 132, 11372-11378.

35.  Q. Zhang, C. Cobley, J. Zeng, L.-P. Wen, J. Chen, Y. Xia*, Dissolving Ag from Au-Ag alloy nanoboxes with H2O2: A method for both tailoring the optical properties and measuring the H2O2 concentration. Journal of Physical Chemistry C 2010, 114, 6396-6400.

36.  Q. Zhang§, W. Yang§, N. Man, F. Zheng, Y. Shen, K. Sun, Y. Li, L. Wen*, Autophagy-mediated chemosensitization in cancer cells by fullerene C60 nanocrystals. Autophagy 2009, 5, 1107-1117.

37.  Q. Zhang, C. Cobley, L. Au, M. McKiernan, A. Schwartz, L.-P. Wen, J. Chen, Y. Xia*, Production of Ag nanocubes on a scale of 0.1 g per batch by protecting the NaHS-mediated polyol synthesis with argon. ACS Applied Materials & Interfaces 2009, 1, 2044-2048. 


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