生命科学学院

学术成果

主持或参与的科研项目:

1. 重点研发“虾贝参蟹绿色优质养殖营养调控机制和精准饲料技术”，课题骨干，2024-2027

2. 国家虾蟹产业技术体系“淡水蟹营养需求与饲料”岗位科学家，2023-2025

3. 第八届中国科协青年人才托举工程，主持，2022-2024

4. 上海市“科技创新行动计划”启明星计划，主持，2022-2025

5. 华东师范大学紫江青年学者科研启动经费项目，主持，2021-2027

6.国家自然科学基金面上项目，主持，2022-2025

7.国家自然科学基金青年基金，2019-2021

8.上海市青年科技英才扬帆计划，主持，2018-2021

9.上海市“晨光计划”，主持，2018-2020

10. 华东师范大学晨晖学者科研启动经费项目，主持，2017-2021

发表论文：

第一或通讯作者论文：

51. Zhu, J., Chen, L., Huang, Y., Zhang, F., Pan, J., Li, E., Qin, J., Qin, C., Wang, X.* 2022. New insights into the influence of myo-inositol on carbohydrate metabolism during osmoregulation in Nile tilapia (Oreochromis niloticus). Animal Nutrition, 10, pp. 86-98.

50. Song, Y., Wang, X.*, Bu, X., Huang, Q., Qiao, F., Chen, X., Shi, Q., Qin, J., Chen, L.* 2022. A comparation between different iron sources on growth performance, iron utilization, antioxidant capacity and non-specific immunity in Eriocheir sinensis. Animal Feed Science and Technology, 288, No. 115300. (共同通讯)

49. Liu, S., Li, X., Wang, X.*, Bu, X., Li, E., Zhang, M., Qin, C., Qin, J.G., Chen, L.* 2022. Molting, tissue calcium‑phosphorus deposition and immunity of juvenile Chinese mitten crab (Eriocheir sinensis) fed different levels of calcium and vitamin D3. Aquaculture, 554, No. 738124. (共同通讯)

48. Huang, Q., You, J., Wang, X.*, Bu, X., Song, Y., Zhang, C., Du, Z., Shi, Q., Qin, J., Chen, L.* 2022. Effect of vitamin A supplement on the growth performance, antioxidant status, and lipid accumulation of Chinese mitten crab Eriocheir Sinensis fed different lipid levels. Aquaculture, 554, No. 738123. (共同通讯)

47. Zhang, C., He, J., Wang, X.*, Su, R., Huang, Q., Qiao, F., Qin, C., Qin, J., Chen, L.* 2022. Dietary gamma-aminobutyric acid (GABA) improves non-specific immunity and alleviates lipopolysaccharide (LPS)-induced immune overresponse in juvenile Chinese mitten crab (Eriocheir sinensis). Fish and Shellfish Immunology, 124, pp. 480-489. (共同通讯)

46. Bu, X., Song, Y., Huang, Q., Liu, S., Cai, X., Wang, X.*, Shi, Q., Du, Z., Qin, J.G., Chen, L.* 2022. Regulatory role of myo-inositol in vegetable oil-mediated lipid metabolism and health of Chinese mitten crab (Eriocheir sinensis). Aquaculture, 552, No. 738002. (共同通讯)

45. Bu, X., Wang, X.*, Lin, Z., Wang, C., Li, L., Liu, S., Shi, Q., Qin, J.G., Chen, L.*2022. Myo-inositol improves growth performance and regulates lipid metabolism of juvenile Chinese mitten crab (Eriocheir sinensis) fed different percentage of lipid. British Journal of Nutrition, 127 (5), pp. 666-678. (共同通讯)

44. Zhang, F., Li, D., Yang, Y., Zhang, H., Zhu, J., Liu, J., Bu, X., Li, E., Qin, J., Yu, N.*, Chen, L., Wang, X.* 2022. Combined effects of polystyrene microplastics and copper on antioxidant capacity, immune response and intestinal microbiota of Nile tilapia (Oreochromis niloticus). Science of the Total Environment, 808, No. 152099. (共同通讯)

43. Huang, Q., Wang, X.*, Liu, J., Wang, H., Miao, Y., Zhang, C., Zhang, M., Qin, C., Qin, J., Chen, L.* 2022. Effect of Vitamin A Supplementation on Growth Performance, Lipid Deposition, Antioxidant Ability, and Immunity in Juvenile Chinese Mitten Crab Eriocheir sinensis Fed Diet with Fish Oil Totally Replaced by Palm Oil. Aquaculture Nutrition, 2022, No. 3746245. (共同通讯)

42. Bu, X., Song, Y., Pan, J., Wang, X.*, Qin, C., Jia, Y., Du, Z., Qin, J.G., Chen, L.*, 2022. Toxicity of chronic copper exposure on Chinese mitten crab (Eriocheir sinensis) and mitigation of its adverse impact by myo-inositol. Aquaculture, 547, No.737511.(共同通讯)

41. Huang, Q., Wang, X.*, Bu, X., Song, Y., You, J., Zhang, C., Qin, C., Qin, J., Chen, L.*, 2022. Dietary vitamin A affects growth performance, immunity, antioxidant capacity, and lipid metabolism of juvenile Chinese mitten crab Eriocheir sinensis. Aquaculture, 548, No.737556.(共同通讯)

40. Song, Y., Wang, X.*, Huang, Q., Wang, X., Lin, Z., Qiao, F., Shi, Q., Qin, J., Chen, L.*, 2021. Evaluation of the optimum dietary iron level and its immunomodulatory effects on juvenile Chinese mitten crab, Eriocheir sinensis. Aquaculture, 544, No. 737122.(共同通讯)

39. Liu, S., Wang, X.*, Bu, X., Lin, Z., Li, E., Shi, Q., Zhang, M., Qin, J.G., Chen, L.*, 2021. Impact of Dietary Vitamin D3Supplementation on Growth, Molting, Antioxidant Capability, and Immunity of Juvenile Chinese Mitten Crabs (Eriocheir sinensis) by Metabolites and Vitamin D Receptor. Journal of Agricultural and Food Chemistry, 69 (43), pp. 12794-12806.(共同通讯)

38. Lin, Z., Wang, X.*, Bu, X., Jia, Y., Shi, Q., Du, Z., Qin, J., Chen, L.*, 2021. Dietary phosphatidylcholine affects growth performance, antioxidant capacity and lipid metabolism of Chinese mitten crab (Eriocheir sinensis). Aquaculture, 541, No. 736814.(共同通讯)

37. Liu, S., Wang, X.*, Bu, X., Zhang, C., Qiao, F., Qin, C., Li, E., Qin, J.G., Chen, L.*, 2021. Influences of dietary vitamin D3 on growth, antioxidant capacity, immunity and molting of Chinese mitten crab (Eriocheir sinensis) larvae. Journal of Steroid Biochemistry and Molecular Biology, 210, No. 105862.(共同通讯)

36. Wang, C., Pan, J., Wang, X.*, Cai, X., Lin, Z., Shi, Q., Li, E., Qin, J.G., Chen, L.*, 2021. N-acetylcysteine provides protection against the toxicity of dietary T-2 toxin in juvenile Chinese mitten crab (Eriocheir sinensis). Aquaculture, 538, No. 736531.(共同通讯)

35. Wang, N., Wang, X.*, Lin, Z., Chen, X., Bu, X., Liu, S., Lei, Y., Shi, Q., Qin, J., Chen, L.*, 2021. Effects of dietary Zn on growth, antioxidant capacity, immunity and tolerance to lipopolysaccharide challenge in juvenile Chinese mitten crab Eriocheir sinensis. Aquaculture Research. (共同通讯)

34. Bu, X., Zhu, J., Liu, S., Wang, C., Xiao, S., Lu, M., Li, E., Wang, X.*, Qin, J.G., Chen, L.*, 2021. Growth, osmotic response and transcriptome response of the euryhaline teleost, Oreochromis mossambicus fed different myo-inositol levels under long-term salinity stress. Aquaculture, 534, No. 736294. (共同通讯)

33. Zhu J., Wang X.*, Bu X., Wang C., Pan J., Li E., Shi Q., Zhang M., Qin J.G., Chen L.*,2021. Relationship between myo-inositol synthesis and carbohydrate metabolism changes in Mozambique tilapia (Oreochromis mossambicus) under acute hypersaline stress. Aquaculture, 532, No. 736005.(共同通讯)

32. Lei, Y., Sun, Y., Wang, X.*, Lin, Z., Bu, X., Wang, N., Du, Z., Qin, J., Chen, L.*, 2021. Effect of dietary phosphorus on growth performance, body composition, antioxidant activities and lipid metabolism of juvenile Chinese mitten crab (Eriocheir sinensis). Aquaculture, 531, No. 735856. (共同通讯)

31. Lin, Z., Bu, X., Wang, N., Lei, Y., Liu, S., Wang, X.*, Gu, Z., Du, Z., Qin, J., Chen, L.*, 2021. Dietary phospholipid alleviates the adverse effects of high-lipid diet in Chinese mitten crab (Eriocheir sinensis). Aquaculture, 531, No. 735899. (共同通讯)

30. Zhang, C., Wang, X.*, Wang, C., Song, Y., Pan, J., Shi, Q., Qin, J., Chen, L.*, 2021. Gamma-aminobutyric acid regulates glucose homeostasis and enhances the hepatopancreas health of juvenile Chinese mitten crab (Eriocheir sinensis) under fasting stress. General and Comparative Endocrinology, 303, No. 113704. (共同通讯)

29. Qi, C., Wang, X.*, Han, F., Chen, X., Li, E., Zhang, M., Qin, J.G., Chen, L., 2021. Dietary arginine alle viates the oxidative stress, inflammation and immunosuppression of juvenile Chinese mitten crab Eriocheir sinensis under high pH stress. Aquaculture Reports, 19, No. 100619.(共同通讯)

28. Zhu, J., Pan, J., Wang, X.*, Huang, Y., Qin, C., Qiao, F., Qin, J., Chen, L.*, 2020. Alleviation of the adverse effect of dietary carbohydrate by supplementation of myo-inositol to the diet of nile tilapia (Oreochromis niloticus). Animals, 10, No. 2190.(共同通讯)

27. Bu, X., Lin, Z., Liu, S., Wang, C., Wang, N., Lei, Y., Zhu, J., Wang, X.*, Qin, J.G., Chen, L.*, 2020. Effects of myo-inositol on growth performance, body composition, antioxidant status, non-specific immunity and lipid metabolism of juvenile Chinese mitten crab (Eriocheir sinensis). Aquaculture Nutrition, 26, 1623-1635.(共同通讯)

26. Lin, Z., Qi, C., Han, F., Chen, X., Qin, C., Wang, C., Wang, X.* , Qin, J., Chen, L.,* 2020. Selecting suitable phospholipid source for female Eriocheir sinensis in pre-reproductive phase. Aquaculture, 528 (共同通讯)

25. Wang, C., Wang, X.* , Huang, Y., Bu, X., Xiao, S., Qin, C., Qiao, F., Qin, J.G., Chen, L.*, 2020. Effects of dietary T-2 toxin on gut health and gut microbiota composition of the juvenile Chinese mitten crab (Eriocheir sinensis). Fish and Shellfish Immunology, 106, pp. 574-582. (共同通讯)

24. Wang, X., Huang, Z., Wang, C., Qi, C., Gu, Z., Li, E., Qin, J.G., Chen, L.*, 2020 A Comparative Study on Growth and Metabolism of Eriocheir sinensis Juveniles Under Chronically Low and High pH Stress. Frontiers in Physiology, 11

23. Han, F., Xu, C., Qi, C., Lin, Z., Li, E., Wang, C., Wang, X.* , Qin, J.G., Chen, L.*, 2020. Sodium butyrate can improve intestinal integrity and immunity in juvenile Chinese mitten crab (Eriocheir sinensis) fed glycinin. Fish and Shellfish Immunology, 102, pp. 400-411. (共同通讯)

22. Wang, C., Wang, X.*, Xiao, S., Bu, X., Lin, Z., Qi, C., Qin, J.G., Chen, L.*, 2020. T-2 toxin in the diet suppresses growth and induces immunotoxicity in juvenile Chinese mitten crab (Eriocheir sinensis). Fish and Shellfish Immunology, 97, pp. 593-601 (共同通讯)

21. Lin, Z., Han, F., Lu, J., Guo, J., Qi, C., Wang, C., Xiao, S., Bu, X., Wang, X.* , Qin, J., Chen, L.*, 2020. Influence of dietary phospholipid on growth performance, body composition, antioxidant capacity and lipid metabolism of Chinese mitten crab, Eriocheir sinensis. Aquaculture, 516 (共同通讯)

20. Han, F., Qi, C., Lin, Z., Jia, Y., Yang, L., Lu, J., Wang, X.*,Li, E., Qin, J.G., Chen, L.*, 2020. Improvement of dietary N-acetylcysteine on growth inhibition and intestinal damage induced by β-conglycinin in juvenile Chinese mitten crabs (Eriocheir sinensis). Aquaculture, 514 (共同通讯)

19. Lu, J., Bu, X., Xiao, S., Lin, Z., Wang, X.* , Jia, Y., Wang, X., Qin, J.G., Chen, L.*, 2019. Effect of single and combined immunostimulants on growth, anti-oxidation activity, non-specific immunity and resistance to Aeromonas hydrophila in Chinese mitten crab (Eriocheir sinensis). Fish and Shellfish Immunology, 93, pp. 732-742. (共同通讯)

18. Lu J, Qi C, LimBu S.M., Han F, Yang L, Wang X*, Qin J.G., Chen L*, 2019. Dietary mannan oligosaccharide (MOS) improves growth performance, antioxidant capacity, non-specific immunity and intestinal histology of juvenile Chinese mitten crabs (Eriocheir sinensis). Aquaculture, 510: 337-346.(共同通讯)

17. Wang X1, Li Q1, Wang J, Li E, Qin J.G., Chen L*, 2019. Effects of dietary alpha-linolenic acids on growth performance, lipid metabolism and antioxidant responses of juvenile Russian sturgeon Acipenser gueldenstaedtii. Aquaculture nutrition, 25: 184-193.(共同第一)

16. Wang X , Shen Z, Wang C, Li E, Qin J.G., Chen L*, 2019. Dietary supplementation of selenium yeast enhances the antioxidant capacity and immune response of juvenile Eriocheir Sinensis under nitrite stress. Fish and shellfish immunology, 87: 22-31.

15. Xu F, Xu C, Xiao S, Lu M, Limbu S.M., Wang X*, Du Z, Qin J.G., Chen L*, 2019. Effects of α-lipoic acid on growth performance, body composition, antioxidant profile and lipid metabolism of the GIFT tilapia (Oreochromis niloticus) fed high-fat diets. Aquaculture Nutrition, 25: 585-596.(共同通讯)

14. Yu N1, Ding Q1, Li E, Qin J.G, Chen L, Wang X*, 2018. Growth, energy metabolism and transcriptomic responses in Chinese mitten crab (Eriocheir sinensis) to benzo[α]pyrene (BaP) toxicity. Aquatic Toxicology, 203: 150-158.

13. Li M1, Wang X1, Qi C, Li E, Qin J.G, Chen L*, 2018. Metabolic response of Nile tilapia (Oreochromis niloticus) to acute and chronic hypoxia stress. Aquaculture, 495: 187-195. (共同第一)

12. Xu C, Li E*, Xu Z, Su Y, Lu M, Qin J, Chen L, Wang X*, 2018.Growth and Stress Axis Responses to Dietary Cholesterol in Nile Tilapia (Oreochromis niloticus) in Brackish Water. Frontiers in Physiology, doi.10.3389/fphys.2018.00254. (共同通讯)

11. Liu Y, Li E*, Xu C, Su Y, Qin J, Chen L, Wang X*, 2018.Brain Transcriptome Profiling Analysis of Nile Tilapia (Oreochromis niloticus) Under Long-Term Hypersaline Stress. Frontiers in Physiology,doi.10.3389/fphys.2018.00219.(共同通讯)

10. Wang X , Kültz D, 2017.Osmolality/ salinity responsive enhancers (OSREs) control induction ofosmoprotective genes in euryhaline fish. Proceedings of the National Academy ofSciences. E2729–E2738.

9. Wang X, Kültz D, 2016.Development of a reporter assay for identifying osmotically responsiveenhancers in euryhaline fish. The FASEB Journal 30(1) Supplement 977.3.

8. Wang X, Li E, Xu Z, Li T, Xu C,Chen L. 2017(Jan). Molecular Response of Carbohydrate Metabolism to Dietary Carbohydrate and Acute Low Salinity Stress in Pacific White Shrimp Litopenaeus vannamei. Turkish Journal ofFisheries and Aquatic Sciences DOI: 10.4194/1303-2712-v17_1_18.

7. Wang X, Li E, Chen L, 2016. A Review of Carbohydrate Nutrition and Metabolism in Crustaceans. North AmericanJournal of Aquaculture 78: 178-187.

6. Wang X, Li E, Chen K, Wang S, LiT, Xu C, Yu N, Qin JG, Chen L. 2017 (Feb). Response of facilitative glucosetransporter 1 to salinity stress and dietary carbohydrate nutrition in whiteshrimp Litopenaeus vannamei.Aquaculture Nutrition DOI: 10.1111/anu.12364.

5. Wang X, Wang S, Li C, Chen K,Qin JG, Chen L, Li E. 2015. Molecular Pathway and Gene Responses of the PacificWhite Shrimp Litopenaeus vannamei toAcute Low Salinity Stress. Journal of Shellfish Research 34(3):1037-1048.

4. Wang X, Li E, Wang S, Qin JG,Chen X, Lai Q, Chen K, Xu C, Gan L, Yu N, Du Z, Chen L. 2015. Protein-sparingeffect of carbohydrate in the diet of white shrimp Litopenaeus vannamei at low salinity. Aquaculture Nutrition21(6):904-912.

3. Wang X, Li E, Qin JG, Wang S,Chen X, Cai Y, Chen K, Hou Y, Yu N, Zhang M, Du Z, Chen L. 2015. Growth, body composition, and ammonia tolerance of juvenile white shrimp Litopenaeus vannamei fed dietscontaining different carbohydrate levels at low salinity. Journal of ShellfishResearch 33(2):511-517.

2. Wang X, Li E, Xiong Z, Chen K,Yu N, Du Z, Chen L. 2014. Low salinity decreases the tolerance to twopesticides, beta-cypermethrin and acephate, of white-leg shrimp, Litopenaeus vannamei. Journal ofAquaculture Research and Development 4(5).

1. Wang X, Li C, Xu C, Qin JG, WangS, Chen X, Cai Y, Chen K, Gan L, Yu N, Du Z, Chen L. 2014. Growth, bodycomposition, ammonia tolerance and hepatopancreas histology of white shrimp Litopenaeus vannamei fed dietscontaining different carbohydrate sources at low salinity. Aquaculture ResearchDOI: 10.1111/are.12650.

参与发表论文：

1. Xu C, Wang X, Han F, Qi C, Li E, Guo J, Qin J.G., Chen L*, 2019. α-lipoic acid regulate growth, antioxidant status and lipid metabolism of Chinese mitten crab Eriocheir sinensis: Optimum supplement level and metabonomics response. Aquaculture, 506: 94-103.

2. Han F, Wang X, Guo J, Qi C, Xu C, Luo Y, Li E, Qin J.G., Chen L*, 2019. Effects of glycinin and β-conglycinin on growth performance and intestinal health in juvenile Chinese mitten crabs (Eriocheir sinensis). Fish and shellfish immunology, 84: 269-279.

3. Ma Q, Wang X, Cui Y, Zhang N, Qin J, Du Z, Chen L,2018. Untargeted GC-MS metabolomics reveals metabolic differences in the Chinese mitten-hand crab (Eriocheir sinensis) fed with dietary palm oil or olive oil. Aquaculture Nutrition.

4. Wang H, Zhu H, Wang X, Li E, Du Z, Qin J, Chen L, 2018. Comparison of copper bioavailability in copper-methionine, nano-copper oxide and copper sulfate additives in the diet of Russian sturgeon Acipenser gueldenstaedtii. Aquaculture, 482, 146-154.

5. Chen Y, Liu W, Wang X, Li E, Qiao F, Qin J, Chen L, 2018. Effect of dietary lipid source and vitamin E on growth, non-specific immune response and resistance to Aeromonas hydrophila challenge of Chinese mitten crab Eriocheir sinensis. Aquaculture research, DOI: 10.1111/are.13659.

6. Li E, Xu C, Wang X, Wang S, Zhao Q, Zhang M, Qin J, Chen L, 2018. Gut Microbiota and its Modulation for Healthy Farming of Pacific White Shrimp Litopenaeus vannamei. Reviews in Fisheries Science & Aquaculture, 26(3) 1-19.

7. Li E, Wang X, Chen K, Xu C, Qin JG, Chen L. 2015. Physiological changeand nutritional requirement of Pacific white shrimp Litopenaeus vannamei at low salinity. Reviews in Aquaculture.

8. Wang Y, Li E,Yu N, Wang X, Cai C, Tang B, Chen L,Wormhoudt AV. 2012. Characterization and expression of glutamate dehydrogenasein response to acute salinity stress in the Chinese mitten crab, Eriocheirsinensis. PLoS ONE 7(5), e37316.

9. Chen K, Li E, Gan L, Wang X,Xu C, Lin H, Qin JG, Chen L. 2014. Growthand lipid metabolism of the pacific white shrimp Litopenaeus vannamei atdifferent salinities. Journal of Shellfish Research 33(3):825-832.

10. Chen K, Li E, Li T, Xu C, WangX, Lin H, Qin JG, Chen L. 2015a. Transcriptomeand molecular pathway analysis of the hepatopancreas in the Pacific whiteshrimp Litopenaeus vannamei under chronic low-salinity stress. PLoS ONE10(7),e0131503.

11. Chen K, Li E, Xu C, Wang X,Lin H, Qin JG, Chen L. 2015b. Evaluationof different lipid sources in diet of pacific white shrimp Litopenaeusvannamei at low salinity. Aquaculture Reports 2:163-168.

12. Li E, Wang S, Li C, Wang X, Chen K, Chen L. 2014.Transcriptome sequencing revealed the genes and pathways involved in salinitystress of Chinese mitten crab, Eriocheir sinensis. Physiol Genomics.doi: 10.1152/physiolgenomics.00191.2013

13. Gan L, Xu Z, Ma J, Xu C, Wang X, Chen K, Chen L,Li E. 2016. Effects of salinity on growth, body composition, muscle fatty acidcomposition, and antioxidant status of juvenile Nile tilapia Oreochromisniloticus (Linnaeus, 1758). Journal of Applied Ichthyology. 32(2):372-374.

14. Xu Z, Gan L, Li T, Xu C, Chen K, Wang X, Qin JG,Chen L, Li E. 2015. Transcriptome profiling and molecular pathway analysis ofgenes in association with salinity adaptation in Nile tilapia Oreochromisniloticus. PLoS ONE 10(8):e0136506.

15. Xu C, Li E, Xu Z, Wang S, Chen K, Wang X, Li T,QIN JG, Chen L. 2016. Molecular characterization and expression ofAMP-activated protein kinase in response to low-salinity stress in the Pacificwhite shrimp Litopenaeus vannamei. Comparative Biochemistry andPhysiology Part - B: Biochemistry and Molecular Biology 198, 79-90.

16. Xu C, Li E, Liu Y, Wang S, WangX, Chen K, Qin JG, Chen L. 2016. Effectof dietary lipid level on growth, lipid metabolism and health status of thePacific white shrimp Litopenaeus vannameiat two salinities. DOI:10.1111/anu.12548.

17. 王悦如, 李二超, 陈立侨, 王晓丹, 张凤英, 高露姣, 龙丽娜. 急性高渗胁迫对中华绒螯蟹雄蟹组织中可溶性蛋白质、血蓝蛋白、血糖与肝糖原含量的影响. 水生生物学报 2012;36(6):1056-1062.

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