个人资料
教育经历工作经历个人简介李小方,华东师范大学,生命科学学院,教授。2000年在中国科学院上海植物生理研究所获博士学位。2000.7至今,在华东师范大学生物系任教。期间2001-2003在美国Case Western Reserve University生物化学系作博士后研究。从事多种因子介导基因表达调控机理的研究。近年来主要工作集中在植物的开花调控、程序性细胞死亡、抗性生理与遗传调控方面,先后主持和参加完成国家自然科学基金课题、863项目、上海市科委和农委课题十几项。发表学术论文近40篇。 社会兼职上海市植物生理学会常务理事和副秘书长 研究方向1 植物细胞死亡调控和抗性遗传 以模式植物拟南芥为主,探索不同逆境下植物细胞内环境稳态调控机制,并开展调控程序性细胞死亡和细胞自噬的功能基因在经济作物中的应用研究。 2 植物开花调控 主要工作集中在植物的休眠、开花与抗性转换机理的研究方面,以中国水仙等花卉为材料,探究温度对其休眠开花调控的分子机制,为使精细调控和开发四季开花的水仙成为可能。 招生与培养开授课程主讲本科生课程 《植物生理学》(必修) 《植物生理学实验》 (必修) 《普通生物学》(菁英班/必修) 《现代植物生理学研究方法及进展》 主讲研究生课程 《植物分子生物学》 (选修) 《植物发育生物学》 (选修) 科研项目1)“拟南芥与温度相关的突变基因LLS的功能研究”(30771155),国家自然科学基金(2008.1-2010.12) 2)“拟南芥AtGAAPs 对非生物胁迫诱导的程序性细胞死亡与植株整体抗性的调控机制”(31670271),国家自然科学基金(2017/01-2020/12) 3)“崇明水仙休眠调节的分子机制”(09JC1405100), 上海市科委基础重点项(2009.9-2012.9) 4)雪莲花青素合成关键基因的分离克隆及离体细胞的遗传转化(084958015)上海市西部合作项目(2008.10-20010.12) 5)“优质芦笋种苗生产和种质保存及创新的关键技术研究”(07DZ12043),上海市科委专项重点项目(2007.9-2009.9) 6)“花椰菜花球形成与基因间的关系”(04ZR14039),上海市自然科学基金 (2004.11-2006.11)。 7)“崇明水仙提纯复壮及产业化关键技术的研究”(沪农科攻字2005第1-2),上海市科技兴农重点攻关项目(2005.12-2008.12) 学术成果近期代表论文有: 1.Manli Zhu†, Xiaohan Tang†, Zhiying Wang†, Wenqi Xu, Yan Zhou, Wei Wang, Xin Li, Rui Li, Kun Guo, Yue Sun, Wei Zhang, Ling Xu, Xiaofang Li*.Arabidopsis GAAPs interacting with MAPR3 modulate IRE1-dependent pathway upon endoplasmic reticulum stress. Journal of Experimental Botany, 2019,70(211):6113-6125. 07 September 2019. 2.Wei Wang†, Xin Li†, Manli Zhu, Xiaohan Tang, Zhiying Wang, Kun Guo, Yan Zhou, Yue Sun, Wei Zhang, Xiaofang Li*. Arabidopsis GAAP1 to GAAP3 Play Redundant Role in Cell Death Inhibition by Suppressing the Upregulation of Salicylic Acid Pathway under Endoplasmic Reticulum Stress. Front. Plant Sci., 27 August 2019 | https://doi.org/10.3389/fpls.2019.01032 3.Kun Guo‡, Wei Wang‡, Weiwei Fan, Zhiying Wang, Manli Zhu, Xiaohan Tang, Wenting Wu, Xue Yang, Xinghua Shao†, Yue Sun, Wei Zhang and Xiaofang Li*. Arabidopsis GAAP1 and GAAP3 Modulate the Unfolded Protein Response and the Onset of Cell Death in Response to ER Stress. Front. Plant Sci., 16 March 2018 |https://doi.org/10.3389/fpls.2018.00348 4.Xiao-Fang Li *, Wen-Ting Wu, Xue-Ping Zhang, Yan Qiu, Wei Zhang, Rui Li, Jing Xu, Yue Sun, Yang Wang, Ling Xu. Narcissus tazetta SVP-like gene NSVP1 affects flower development in Arabidopsis. J. Plant Physiology 2015, 173:89-96 5.Xiao-Fang Li *, Lin-Yan Jia, Jing Xu, Xin-Jie Deng, Yang Wang, Wei Zhang, Xue-Ping Zhang, Qi Fang, Dong-Mei Zhang, Yue Sun, Ling Xu. FT-like NFT1 gene may play a role in flower transition induced by heat accumulation in Narcissus tazetta var. chinensis. Plant Cell Physiol 2013, 54(2) :270-281 6.Xiao-Fang Li *, Jing Xu, Ru Yang, Lin-Yan Jia, Xin-Jie Deng, Li-Jun Xiong, Xue-Ping Zhang, Qi Fang, Wei Zhang, Yue Sun, Ling Xu. Analysis of B-Class Genes NAP 7.Xiao-Fang Li *,Xing-Hua Shao, Xin-Jie Deng, Yang Wang, Xue-Ping Zhang, Lin-Yan Jia, Jing Xu, Dong-Mei Zhang, Yue Sun, Ling Xu. Necessity of high temperature for the dormancy release of Narcissus tazetta var. chinensis. J. Plant Physiology, 2012, 169(14):1340–1347 8.Xinghua Shao, Ru Yang, Jingyu Wang, Qi Fang, Bin Yao, Yang Wang, Yue Sun, Xiaofang Li*. The Altered Responses of a New Mutant long life span 1 to Cytokinin in Arabidopsis thaliana. Journal of Genetics and Genomics, 2012, 39(3) :139-148 9.Deng Xinjie, Xiong Lijun, Wang Yang, Sun Yue, *Li Xiao Fang. Ectopic expression of a Chinese narcissus (Narcissus tazetta var. chinensis Roem.) AGAMOUS homolog NTAG1 accelerated earlier flowering and senescence in Arabidopsis.Molecular Plant Breeding, 2011, 2(3), pp 1-8http://bio.sophiapublisher.com/html-86-5-mpb 10.Xiao-Fang Li *, Yu-Ju Li, Ying-Hui An, Li-Jun Xiong, Xing-Hua Shao, Yang Wang and Yue Sun. AKINβ1 is involved in the regulation of Nitrogen metabolism and sugar signaling in Arabidopsis. Journal of Integrative Plant Biology 2009, 51(5), 513-520 11.Gao C, Li Xiaofang, Lam M, Liu Y, Chakraborty S, Kao HY. CRM1 mediates nuclear export of HDAC7 independently of HDAC7 phosphorylation and association with 14-3-3s. FEBS Lett. 2006, 580(21): 96-104. (SCI, IF:3.541) 12.Chakraborty S, Reineke EL, Lam M, Li X, Liu Y, Gao C, Khurana S, Kao HY. Alpha-actinin 4 potentiates myocyte enhancer factor-2 transcription activity by antagonizing histone deacetylase 7. J. Biol. Chem. 2006,281 (46): 35070-80. 13.Yue Sun, Yang Yang,Zheng Yuan, Jutta Ludwig Müller, Chen Yu, Yanfei Xu, Xinghua Shao, Xiaofang Li, Eva L Decker, Ralf Reski and Hai Huang. Overexpression of the Arabidopsis gene UPRIGHT ROSETTE reveals a homeostatic control for indole-3-acetic acid (IAA). Plant Physiol. 2010 July; 153(3): 1311–1320. 14.Wenqian Zhao, Zeling Li, Yongyue Hu, Min Wang, Shirui Zheng, Qiuping Li, Youfang Wang, Lin Xu, Xiaofang Li, Ruiliang Zhu, Ralf Reski, Yue Sun. Development of a method for protonema proliferation of peat moss (Sphagnum squarrosum) through regeneration analysis. New Phytologist. 2019, 221: 1160–1171 15. 朱蔓莉#, 王智颖#, 唐小寒, 郭坤, 王薇, 孙越, 张伟, 李小方*。异源表达N-端融合eYFP标签的GAAPs增强拟南芥对ER胁迫敏感性。植物生理学报2018, 54 (6): 983–990 16.主编“十一五”国家级规划教材《植物生理学实验指导》(第4版和第5版),北京,高等教育出版社 荣誉及奖励1.上海市申银万国奖教金,2005 2.华东师范大学“三八红旗手”,2008 3.在研究中学习,在学习中研究”上海市教学成果二等奖,2009(植物学教学团队奖) 4.“经典植物学教学的传承与创新”上海市教学成果一等奖,2014(植物学教学团队奖) 5.“植物生理学实验”获华师大本科教学课程设计比赛优胜奖,2017 |